Department of Eating and Weight Disorders, Villa Garda Hospital, Garda, Italy.
Int J Eat Disord. 2019 Sep;52(9):1042-1046. doi: 10.1002/eat.23122. Epub 2019 Jun 14.
The study aimed to establish the outcomes and predictors of change in a cohort of adolescents with anorexia nervosa treated via enhanced cognitive behavioral therapy (CBT-E) in a real-world clinical setting.
Forty-nine adolescent patients with anorexia nervosa were recruited from consecutive referrals to a clinical eating disorder service offering outpatient CBT-E. Body Mass Index centiles and Eating Disorder Examination Questionnaire, Brief Symptom Inventory, and Clinical Impairment Assessment scores were recorded at admission, at the end of treatment, and at 20-week follow-up.
Thirty-five patients (71.4%) who finished the program showed both considerable weight gain and reduced scores for clinical impairment and eating disorder and general psychopathology. Changes remained stable at 20 weeks. No baseline predictors of drop-out or treatment outcomes were detected.
Based on these results, CBT-E seems suitable for adolescent patients with anorexia nervosa seeking treatment in a real-world clinical setting.
本研究旨在为接受强化认知行为疗法（CBT-E）治疗的青少年厌食症患者队列建立结局和变化预测因素，该研究是在真实临床环境中进行的。
从提供门诊 CBT-E 的临床饮食失调服务连续转介的青少年厌食症患者中招募了 49 名青少年患者。在入院时、治疗结束时和 20 周随访时记录体重指数百分位数和饮食失调检查问卷、简明症状量表和临床损伤评估分数。
完成该项目的 35 名患者（71.4%）表现出显著的体重增加和临床损伤、饮食障碍和一般精神病理学评分的降低。20 周时，这些变化仍然稳定。未检测到脱落或治疗结果的基线预测因素。
基于这些结果，CBT-E 似乎适合在真实临床环境中寻求治疗的青少年厌食症患者。
