Alaguvelsamy Sujeethra, Pal Singh Sachender, Ramalingam Ravi, Kombupalayam Komarappa Gounder Ramalingam
KKR ENT Hospital & Research Institute, Poonamallee High Road, Kilpauk, Chennai, Tamil Nadu, 600010, India.
KKR ENT Hospital & Research Institute, Poonamallee High Road, Kilpauk, Chennai, Tamil Nadu, 600010, India.
Int J Surg Case Rep. 2020;73:190-195. doi: 10.1016/j.ijscr.2020.07.017. Epub 2020 Jul 15.
Toxic multinodular goiter (MNG) involves an enlarged thyroid gland, is a common cause of hyperthyroidism and when it is accompanied by obstructive symptoms such as dyspnea, it carries an indication for surgery.
We present a case of 47-year old female with multinodular goiter with a rapid increase in size within 2 years. She also reported palpitation, breathlessness on exertion, tachycardia and hand tremor. Computed tomography scan of the neck shows a gross enlargement of thyroid gland across both sides of the neck. The fine needle aspiration cytology and final histopathological examination were suggestive of MNG with adenomatous nodules and toxic changes respectively. A total thyroidectomy was performed and the gland was dissected successfully.
Toxic MNG is most effectively treated by total thyroidectomy, which achieves complete diminution from symptoms.
Surgery for huge goiter is challenging and one should be careful about difficult intubation, altered anatomy and adhesions to the surrounding structures. Recognizing and treating this kind of cases are important, as they constitute a preventable cause of mortality if timely diagnosed and treated.
毒性多结节性甲状腺肿(MNG)表现为甲状腺肿大,是甲状腺功能亢进的常见病因,当伴有呼吸困难等梗阻症状时,具有手术指征。
我们报告一例47岁女性,患有多结节性甲状腺肿,在2年内甲状腺大小迅速增大。她还自述有心悸、劳力性呼吸困难、心动过速和手部震颤。颈部计算机断层扫描显示双侧甲状腺明显肿大。细针穿刺细胞学检查和最终组织病理学检查分别提示为伴有腺瘤样结节和毒性改变的MNG。实施了全甲状腺切除术,甲状腺成功切除。
全甲状腺切除术是治疗毒性MNG的最有效方法,可使症状完全缓解。
巨大甲状腺肿手术具有挑战性,应对困难插管、解剖结构改变以及与周围结构的粘连保持警惕。认识并治疗这类病例很重要,因为如果及时诊断和治疗,它们是可预防的死亡原因。