Department of Public Health, University of North Florida, Jacksonville, FL, USA.
Int J STD AIDS. 2020 Sep;31(10):976-981. doi: 10.1177/0956462420937168. Epub 2020 Jul 21.
Nearly all cases of cervical cancer are attributable to human papillomavirus (HPV), making it a significant women's health issue. Though there have been advances in the prevention of HPV via vaccination, significant barriers continue to suppress vaccination rates for girls. Delaying vaccination until after sexual debut increases a woman's chance of HPV infection, but there has been no quantification of this risk in the literature. The present study sought to address this gap via secondary data analysis with 173 female participants from the 2015-2016 National Health and Nutrition Examination Survey dataset. Results indicate that women in the sample who received the HPV vaccine after their sexual debut were 2.63 times more likely than women who receive the vaccine before their sexual debut to report an HPV diagnosis. These results have clear public and sexual health implications.
几乎所有宫颈癌病例都可归因于人乳头瘤病毒（HPV），这是一个重大的女性健康问题。虽然通过疫苗接种在预防 HPV 方面已经取得了进展，但仍存在重大障碍，持续抑制了女孩的疫苗接种率。将接种疫苗推迟到初次性行为后会增加女性 HPV 感染的机会，但文献中尚未对此风险进行量化。本研究通过对 2015-2016 年全国健康和营养调查数据集的 173 名女性参与者进行二次数据分析来解决这一差距。结果表明，与初次性行为前接种 HPV 疫苗的女性相比，初次性行为后接种 HPV 疫苗的女性报告 HPV 诊断的可能性要高出 2.63 倍。这些结果具有明确的公共卫生和性健康意义。
