George Anju, George Renu, Mathew Ashish J, Telugu Ramesh B
Department of Dermatology, Christian Medical College, Vellore, Tamil Nadu, India.
Department of Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.
Indian Dermatol Online J. 2020 May 10;11(3):413-415. doi: 10.4103/idoj.IDOJ_337_19. eCollection 2020 May-Jun.
Dowling-Degos disease (DDD) is a rare autosomal dominant genodermatosis characterized by reticulate brown-to-black pigmentation of the flexures, pitted perioral acneiform scars, and comedo-like follicular papules on the flexures. The diagnosis is based on characteristic clinical and histopathological features. DDD has been found to occur in association with hidradenitis suppurativa (HS), arthritis, epidermoid cysts, keratoacanthomas, and squamous cell carcinoma. To date, there is only one report of DDD associated with HS and polyarticular arthritis.
道林-迪戈斯病（DDD）是一种罕见的常染色体显性遗传性皮肤病，其特征为屈侧出现网状棕黑色色素沉着、口周有凹陷性痤疮样瘢痕以及屈侧出现粉刺样毛囊丘疹。诊断基于特征性的临床和组织病理学特征。已发现DDD与化脓性汗腺炎（HS）、关节炎、表皮样囊肿、角化棘皮瘤和鳞状细胞癌有关。迄今为止，仅有一篇关于DDD与HS及多关节关节炎相关的报道。
