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Total Cumulative Dose of Methotrexate is Not the Same as Continuous Cumulative Dose: A Clinician's Perspective.

作者信息

Khaitan Binod K, Gupta Savera

机构信息

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian Dermatol Online J. 2020 May 10;11(3):425-427. doi: 10.4103/idoj.IDOJ_361_19. eCollection 2020 May-Jun.

DOI:10.4103/idoj.IDOJ_361_19
PMID:32695708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7367581/
Abstract
摘要

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本文引用的文献

1
Methotrexate and liver fibrosis in people with psoriasis: a systematic review of observational studies.甲氨蝶呤与银屑病患者的肝纤维化：观察性研究的系统评价。
Br J Dermatol. 2014 Jul;171(1):17-29. doi: 10.1111/bjd.12941. Epub 2014 Jul 15.
2
Psoriasis is independently associated with nonalcoholic fatty liver disease in patients 55 years old or older: Results from a population-based study.银屑病与 55 岁及以上患者的非酒精性脂肪性肝病独立相关：一项基于人群的研究结果。
J Am Acad Dermatol. 2014 Mar;70(3):517-24. doi: 10.1016/j.jaad.2013.10.044. Epub 2013 Dec 24.
3
Weekly vs. daily administration of oral methotrexate (MTX) for generalized plaque psoriasis: a randomized controlled clinical trial.每周与每日口服甲氨蝶呤（MTX）治疗泛发性斑块状银屑病：一项随机对照临床试验。
Int J Dermatol. 2011 Oct;50(10):1291-3. doi: 10.1111/j.1365-4632.2011.04967.x.
4
Methotrexate and psoriasis: 2009 National Psoriasis Foundation Consensus Conference.甲氨蝶呤与银屑病：2009年美国国家银屑病基金会共识会议
J Am Acad Dermatol. 2009 May;60(5):824-37. doi: 10.1016/j.jaad.2008.11.906.
5
Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: a systematic literature research.甲氨蝶呤单药治疗类风湿关节炎患者的长期安全性：一项系统文献研究
Ann Rheum Dis. 2009 Jul;68(7):1100-4. doi: 10.1136/ard.2008.093690. Epub 2008 Dec 5.
6
Treatment of psoriatic arthritis and rheumatoid arthritis with disease modifying drugs -- comparison of drugs and adverse reactions.使用改善病情药物治疗银屑病关节炎和类风湿关节炎——药物及不良反应比较
J Rheumatol. 2008 Mar;35(3):472-6. Epub 2008 Jan 15.
7
Liver injury in long-term methotrexate treatment in psoriasis is relatively infrequent.长期使用甲氨蝶呤治疗银屑病时，肝脏损伤相对少见。
Aliment Pharmacol Ther. 2006 Sep 1;24(5):805-11. doi: 10.1111/j.1365-2036.2006.03047.x.
8
Monitoring liver function during methotrexate therapy for psoriasis: are routine biopsies really necessary?甲氨蝶呤治疗银屑病期间的肝功能监测：常规活检真的有必要吗？
Am J Clin Dermatol. 2005;6(6):357-63. doi: 10.2165/00128071-200506060-00003.
9
Liver regeneration: from myth to mechanism.肝脏再生：从神话到机制
Nat Rev Mol Cell Biol. 2004 Oct;5(10):836-47. doi: 10.1038/nrm1489.
10
Monitoring methotrexate-induced hepatic fibrosis in patients with psoriasis: are serial liver biopsies justified?监测银屑病患者中氨甲蝶呤诱导的肝纤维化：连续肝活检是否合理？
Aliment Pharmacol Ther. 2004 Feb 15;19(4):391-9. doi: 10.1046/j.1365-2036.2004.01819.x.