Dermatology and Venereology Department, Erciyes University Medical School, Kayseri, Turkey.
Dermatology and Venerology Department, Kayseri City Hospital, Kayseri, Turkey.
Skin Res Technol. 2021 Jan;27(1):101-107. doi: 10.1111/srt.12917. Epub 2020 Jul 21.
This study aimed to investigate the relationship between skin parameters and CAD.
The study included 50 patients diagnosed with coronary artery disease as the patient group and 45 volunteers without any known coronary artery disease as the control group. The participants' skin TEWL, pH, temperature, electrical capacitance, sebum, and elasticity values were measured using noninvasive methods at the forehead, back, and forearm.
Skin temperature was significantly higher in the back and forehead regions in the patient group. No difference was found between the sebum values of the patient and control groups at the back and forehead. A significantly higher result was obtained for the forearm area. The pH was significantly lower in the patients' forearm, although the obtained values were within the normal range. The TEWL was significantly higher in patients in all three regions. In terms of flexibility, R2 was significantly higher in the back and forehead regions of the patient group, and the R6 was significantly higher in the patient group in all three regions. In addition, there was no correlation between skin parameter and SYNTAX score increase measurements.
It can be suggested that skin sebum and TEWL measurements can be accepted as cheap and noninvasive methods of predicting CAD.
本研究旨在探讨皮肤参数与 CAD 的关系。
研究纳入 50 例冠状动脉疾病患者作为患者组和 45 例无任何已知冠状动脉疾病的志愿者作为对照组。使用非侵入性方法测量前额、背部和前臂的皮肤 TEWL、pH 值、温度、电容、皮脂和弹性值。
患者组背部和前额皮肤温度明显较高。背部和前额皮脂值在患者组和对照组之间无差异。前臂区域的结果明显较高。虽然获得的值在正常范围内，但患者前臂的 pH 值明显较低。在所有三个区域，TEWL 均显著升高。在背部和前额区域，患者组的 R2 明显较高，在所有三个区域，患者组的 R6 明显较高。此外，皮肤参数与 SYNTAX 评分增加测量之间无相关性。
可以认为皮脂和 TEWL 测量可以作为预测 CAD 的廉价、非侵入性方法。
