仓鼠颊囊迟发型超敏反应。

Delayed hypersensitivity in the hamster cheek pouch.

作者信息

Marshack M, Toto P, Kerman R

出版信息

J Immunol Methods. 1977;15(4):325-30. doi: 10.1016/0022-1759(77)90094-1.

Abstract

A method is described for eliciting a delayed hypersensitive cell mediated immune response in the Syrian hamster cheek pouch. Using a sensitizing dose of 0.1% DNCB and a challenge dose of 0.01% DNCB 14 days later resulted in a histologically positive lymphocyte infiltrate in the challenge area. These results indicate that the hamster cheek pouch may not be an immunologically inert site and may be used for cell mediated immunity studies.

摘要

本文描述了一种在叙利亚仓鼠颊囊引发迟发型超敏细胞介导免疫反应的方法。使用0.1%二硝基氯苯致敏剂量，并在14天后使用0.01%二硝基氯苯激发剂量，结果在激发区域出现了组织学上阳性的淋巴细胞浸润。这些结果表明，仓鼠颊囊可能不是一个免疫惰性部位，可用于细胞介导免疫研究。