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东地中海四个国家儿童癌症的经济学:一项比较评估。

Economics of Pediatric Cancer in Four Eastern Mediterranean Countries: A Comparative Assessment.

作者信息

Gheorghe Adrian, Chalkidou Kalipso, Shamieh Omar, Kutluk Tezer, Fouad Fouad, Sultan Iyad, Sullivan Richard

机构信息

Global Health and Development, Imperial College London, London, United Kingdom.

Center for Global Development Europe, London, United Kingdom.

出版信息

JCO Glob Oncol. 2020 Jul;6:1155-1170. doi: 10.1200/GO.20.00041.

Abstract

PURPOSE

Cancer is a leading cause of death among children in the Eastern Mediterranean region, where conflict and economic downturn place additional burden on the health sector. In this context, using economic evidence to inform policy decisions is crucial for maximizing health outcomes from available resources. We summarized the available evidence on the economics of pediatric cancer in Jordan, Lebanon, the occupied Palestinian territory, and Turkey.

METHODS

A scoping review was performed of seven academic databases and gray literature pertaining to pediatric cancer in the four jurisdictions, published between January 1, 2010, and July 17, 2019. Information was extracted and organized using an analytical framework that synthesizes economic information on four dimensions: the context of the health system, the economics of health care inputs, the economics of service provision, and the economic consequences of disease.

RESULTS

Most of the economic evidence available across the four jurisdictions pertains to the availability of health care inputs (ie, drugs, human resources, cancer registration data, and treatment protocols) and individual-level outcomes (either clinical or health-related quality of life). We identified little evidence on the efficiency or quality of health care inputs and of pediatric cancer services. Moreover, we identified no studies examining the cost-effectiveness of any intervention, program, or treatment protocol. Evidence on the economic consequences of pediatric cancer on families and the society at large was predominantly qualitative.

CONCLUSION

The available economic evidence on pediatric cancer care in the four countries is limited to resource availability and, to an extent, patient outcomes, with a substantial gap in information on drug quality, service provision efficiency, and cost-effectiveness. Links between researchers and policymakers must be strengthened if pediatric cancer spending decisions, and, ultimately, treatment outcomes, are to improve.

摘要

目的

癌症是东地中海地区儿童的主要死因,该地区的冲突和经济衰退给卫生部门带来了额外负担。在此背景下,利用经济证据为政策决策提供依据对于从现有资源中最大化健康成果至关重要。我们总结了约旦、黎巴嫩、巴勒斯坦被占领土和土耳其有关儿童癌症经济学的现有证据。

方法

对2010年1月1日至2019年7月17日期间发表的、与这四个管辖区儿童癌症相关的七个学术数据库和灰色文献进行了范围审查。使用一个分析框架提取和整理信息,该框架综合了四个维度的经济信息:卫生系统背景、医疗保健投入经济学、服务提供经济学以及疾病的经济后果。

结果

这四个管辖区现有的大多数经济证据都与医疗保健投入的可用性(即药物、人力资源、癌症登记数据和治疗方案)以及个体层面的结果(临床或与健康相关的生活质量)有关。我们几乎没有找到关于医疗保健投入和儿童癌症服务的效率或质量的证据。此外,我们没有发现任何研究考察任何干预措施、项目或治疗方案的成本效益。关于儿童癌症对家庭和整个社会的经济后果的证据主要是定性的。

结论

这四个国家现有的关于儿童癌症护理的经济证据仅限于资源可用性,在一定程度上还包括患者结果,在药物质量、服务提供效率和成本效益方面的信息存在很大差距。如果要改善儿童癌症的支出决策以及最终的治疗结果,就必须加强研究人员与政策制定者之间的联系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b35/7392699/28bbd991ae4a/GO.20.00041f1.jpg

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