Suppr超能文献

肉类及肉制品会引发氧化应激吗?

Can Meat and Meat-Products Induce Oxidative Stress?

作者信息

Macho-González Adrián, Garcimartín Alba, López-Oliva María Elvira, Bastida Sara, Benedí Juana, Ros Gaspar, Nieto Gema, Sánchez-Muniz Francisco José

机构信息

Nutrition and Food Science Department (Nutrition), Pharmacy School, Complutense University of Madrid, 28040 Madrid, Spain.

Pharmacology, Pharmacognosy and Botany Department, Pharmacy School, Complutense University of Madrid, 28040 Madrid, Spain.

出版信息

Antioxidants (Basel). 2020 Jul 20;9(7):638. doi: 10.3390/antiox9070638.

Abstract

High meat and meat-products consumption has been related to degenerative diseases. In addition to their saturated fatty acids and cholesterol contents, oxidation products generated during their production, storage, digestion, and metabolization have been largely implicated. This review begins by summarizing the concept of meat and meat-products by the main international regulatory agencies while highlighting the nutritional importance of their consumption. The review also dials in the controversy of white/red meat classification and insists in the need of more accurate classification based on adequate scores. Since one of the negative arguments that meat receives comes from the association of its consumption with the increase in oxidative stress, main oxidation compounds (malondialdehyde, thermaloxidized compounds, 4-hydroxy-nonenal, oxysterols, or protein carbonyls) generated during its production, storage, and metabolization, are included as a central aspect of the work. The review includes future remarks addressed to study the effects meat consumption in the frame of diet-gene interactions, stressing the importance of knowing the genetic variables that make individuals more susceptible to a possible oxidative stress imbalance or antioxidant protection. The importance of consumed meat/meat-products in the frame of a personalized nutrition reach in plant-food is finally highlighted considering the importance of iron and plant biophenols on the microbiota abundance and plurality, which in turn affect several aspects of our physiology and metabolism.

摘要

高肉类及肉类产品消费量与退行性疾病有关。除了其饱和脂肪酸和胆固醇含量外,它们在生产、储存、消化和代谢过程中产生的氧化产物也在很大程度上与此有关。本综述首先总结了主要国际监管机构对肉类及肉类产品的概念,同时强调了其消费的营养重要性。该综述还深入探讨了白肉/红肉分类的争议,并坚持需要基于适当评分进行更准确的分类。由于肉类受到的负面争议之一源于其消费与氧化应激增加之间的关联,因此在其生产、储存和代谢过程中产生的主要氧化化合物(丙二醛、热氧化化合物、4-羟基壬烯醛、氧化甾醇或蛋白质羰基)被纳入该研究的核心内容。该综述包括未来的展望,旨在研究肉类消费在饮食-基因相互作用框架中的影响,强调了解使个体更容易受到可能的氧化应激失衡或抗氧化保护影响的遗传变量的重要性。考虑到铁和植物生物酚对微生物群丰度和多样性的重要性,而这又会影响我们生理和代谢的多个方面,最终强调了在个性化营养摄入植物性食物的框架中所消费的肉类/肉类产品的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da36/7402184/ef53a7635ebb/antioxidants-09-00638-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验