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瑞典全国性调查的乳房重建模式。

Breast reconstruction patterns from a Swedish nation-wide survey.

机构信息

Department of Surgical Sciences, Section of Plastic Surgery, Uppsala University, Uppsala University Hospital, Sweden; Department of Surgery, Capio S:t Görans Hospital, Stockholm, Sweden.

Department of Surgical Sciences, Section of Plastic Surgery, Uppsala University, Uppsala University Hospital, Sweden.

出版信息

Eur J Surg Oncol. 2020 Oct;46(10 Pt A):1867-1873. doi: 10.1016/j.ejso.2020.04.030. Epub 2020 May 18.

Abstract

OBJECTIVES

The overall aim of the Swedish Breast Reconstruction Outcome Study was to investigate national long-term outcomes after mastectomy with or without breast reconstruction. The current report evaluates breast reconstruction (BR) patterns in Sweden over time.

MATERIALS AND METHODS

This is a cross-sectional, registry-based study where all women operated with mastectomy 2000, 2005, 2010 were identified (N = 5853). Geographical differences in type of BR were investigated using heatmaps. Distribution of continuous variables were compared using the Mann-Whitney U test, categorical variables were compared using the chi-square test.

RESULTS

Mean age at survey was 69 years (SD=±11.4) and response rate was 50%, responders were on average six years younger than the non-responders and had a more favourable tumor stage (both p < 0.01). Of the 2904 responders, 31% (895/2904) had received a BR: implant-based in 58% (516/895)autologous in 31% (281/895). BR was immediate in 20% (176/895) and delayed in 80% (719/895) women. Women with BR were on average one year older, more often had a normal BMI, reported to be married or had a partner, had a higher educational level and a higher annual income when compared to those without BR (all p < 0.001). The independent factors of not receiving BR were older age and given radiotherapy.

CONCLUSIONS

To our knowledge, this is the first national long-term follow-up study on women undergoing mastectomy with and without BR. Around 30% of the survey responders have had a BR with a significant geographical variation highlighting the importance of information, availability and standardisation of indications for BR.

摘要

目的

瑞典乳房重建结局研究的总体目标是调查乳房切除术(mastectomy)后接受或不接受乳房重建的患者的长期全国性结局。本报告评估了瑞典乳房重建(breast reconstruction,BR)模式随时间的变化。

材料与方法

这是一项基于注册的横断面研究,研究纳入了 2000 年、2005 年和 2010 年接受乳房切除术的所有女性(n=5853)。使用热图研究 BR 类型的地理差异。使用 Mann-Whitney U 检验比较连续变量的分布,使用卡方检验比较分类变量的分布。

结果

调查时的平均年龄为 69 岁(标准差=±11.4),响应率为 50%,响应者比非响应者平均年轻 6 岁,肿瘤分期更有利(均 p<0.01)。在 2904 名应答者中,31%(895/2904)接受了 BR:基于植入物的 BR 占 58%(516/895),自体的 BR 占 31%(281/895)。BR 即时进行的占 20%(176/895),延迟进行的占 80%(719/895)。与未接受 BR 的女性相比,接受 BR 的女性平均年龄更大,更常具有正常 BMI,已婚或有伴侣,教育程度更高,年收入更高(均 p<0.001)。未接受 BR 的独立因素是年龄较大和接受放射治疗。

结论

据我们所知,这是第一项关于接受乳房切除术并接受或不接受 BR 的女性的全国性长期随访研究。约 30%的调查应答者接受了 BR,具有显著的地域差异,突出了 BR 相关信息、可用性和适应证标准化的重要性。

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