Department of Otolaryngology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Acta Otolaryngol. 2020 Sep;140(9):723-727. doi: 10.1080/00016489.2020.1769863. Epub 2020 Jul 23.
Furosemide-loading cervical vestibular-evoked myogenic potential (FVEMP), in which vestibular function is improved diuretics-induced dehydration, can be used to estimate the presence of endolymphatic hydrops, one characteristic of Menière's disease. Inner ear magnetic resonance imaging (MRI) can also reveal endolymphatic hydrops. This study aimed to compare and confirm the usefulness of these two examination methods for the diagnosis of Menière's disease.
Twenty patients with definite unilateral Menière's disease were included. All subjects underwent both, FVEMP and inner ear MRI examinations. The results were then compared statistically between the affected and contralateral ears and among the methods.
FVEMP and inner ear MRI of the cochlea, saccules, and utricles yielded positive results indicative of endolymphatic hydrops in 55.0%, 60.0%, 45.0%, and 45.0% of cases, respectively. The results of FVEMP were more consistent with those of the cochlea ( = 0.8) than with those of the saccules or utricles by inner ear MRI ( = 0.6).
FVEMP appears to be a good and minimally invasive option for evaluating endolymphatic hydrops. However, the combination of FVEMP and inner ear MRI may yield even more accurate evaluations of endolymphatic hydrops.
速尿负荷颈性前庭诱发肌源性电位（FVEMP）可改善利尿剂诱导的脱水引起的前庭功能，可用于评估内淋巴积水的存在，这是梅尼埃病的一个特征。内耳磁共振成像（MRI）也可以显示内淋巴积水。本研究旨在比较和证实这两种检查方法对梅尼埃病诊断的有用性。
纳入 20 例单侧明确诊断为梅尼埃病的患者。所有患者均接受 FVEMP 和内耳 MRI 检查。然后对受累耳和对侧耳以及两种方法的结果进行统计学比较。
FVEMP 和内耳 MRI 对耳蜗、前庭和椭圆囊的检查结果分别显示内淋巴积水的阳性结果为 55.0%、60.0%、45.0%和 45.0%。FVEMP 的结果与耳蜗（ = 0.8）比内耳 MRI 的前庭（ = 0.6）或椭圆囊更一致。
FVEMP 似乎是评估内淋巴积水的一种良好且微创的选择。然而，FVEMP 和内耳 MRI 的联合应用可能对内淋巴积水的评估更准确。
