Department of Pathology, Recep Tayyip Erdoğan University, School of Medicine, RIZE, TURKEY.
Turk Patoloji Derg. 2021;37(1):67-70. doi: 10.5146/tjpath.2020.01499.
Cutaneous squamous cell carcinomas are the second most frequent type of non-melanoma skin cancer. A 78-year-old man with a slow-growing but large nodular lesion on his scalp presented to the hospital. The nodular lesion was excised. Histologically, the lesion was diagnosed as a primary cutaneous myxoid spindle cell squamous cell carcinoma, which is the subject of this case report. Extracellular mucin production is an even less common finding in SCC. We also aim to discuss the histological and immunohistochemical findings for distinguishing MSC SCC from other primary cutaneous and metastatic spindle cell neoplasms with myxoid stroma.
皮肤鳞状细胞癌是第二常见的非黑色素瘤皮肤癌。一位 78 岁的男性头皮上有一个生长缓慢但较大的结节性病变，到医院就诊。结节性病变被切除。组织学上，病变被诊断为原发性皮肤粘液样梭形细胞鳞状细胞癌，这是本病例报告的主题。细胞外粘蛋白产生在 SCC 中更为少见。我们还旨在讨论组织学和免疫组织化学发现，以区分 MSC SCC 与其他具有粘液样基质的原发性皮肤和转移性梭形细胞肿瘤。
