La Trobe University, Melbourne, Australia.
Diakonhjemmet Hospital, Oslo, Norway.
Hip Int. 2021 Nov;31(6):789-796. doi: 10.1177/1120700020943853. Epub 2020 Jul 23.
The primary aim of this study was to determine the prevalence of cam morphology in a cohort of people aged 40-55 years. Secondary aims were to: (1) determine differences in participant characteristics, physical impairments, radiographic and ultrasound appearances of people with and without cam morphology; and (2) explore associations between cam morphology and radiographic measures of hip osteoarthritis (OA).
107 people (68% women; 49 ± 4 years) from the Musculoskeletal pain in Ullensaker (MUST) Study underwent the clinical and imaging examinations. Examinations included questionnaires, hip range, functional task performance, pelvic radiographs and ultrasound. Alpha angle and radiographic hip OA (Kellgren Lawrence (KL) and minimal joint space (MJS)) were determined.
The prevalence of cam morphology was 42% and was bilateral in 47%. People with cam morphology were 6 times more likely to have a KL score ⩾2 (adjusted odds ratio [95% confidence intervals, -value]) 6.386 [1.582-37.646, = 0.012]) and 4 times more likely to have MJS <2.0 mm (adjusted odds ratio 4.032 [1.031-12.639, 0.045]). The prevalence of radiographic OA features ranged from 4-13% in people with cam morphology, and 0-3% in those without. Those with cam morphology also demonstrated reduced hip flexion and rotation range ( = 0.018-0.036) compared with those without. There was no association between ultrasonic features and patient reported outcomes, and cam morphology.
In a cohort aged 40-55 years, the prevalence of cam morphology was high (42%), with a significant relationship between cam morphology and radiographic measures of hip OA. Further longitudinal studies should explore the relationship between cam morphology and hip OA in younger people.
本研究的主要目的是确定 40-55 岁人群中凸轮形态的流行率。次要目的是：（1）确定有和没有凸轮形态的参与者的特征、身体损伤、影像学和超声表现的差异；（2）探讨凸轮形态与髋关节骨关节炎（OA）的影像学测量值之间的关联。
来自肌肉骨骼疼痛 Ullensaker 研究（MUST）的 107 人（68%为女性；49±4 岁）接受了临床和影像学检查。检查包括问卷调查、髋关节活动范围、功能任务表现、骨盆 X 线片和超声检查。确定了 alpha 角和放射影像学髋关节 OA（Kellgren Lawrence（KL）分级和最小关节间隙（MJS））。
凸轮形态的患病率为 42%，双侧为 47%。有凸轮形态的人发生 KL 分级 ⩾2 的可能性高 6 倍（校正比值比[95%置信区间，-值]）6.386[1.582-37.646，=0.012]，发生 MJS<2.0mm 的可能性高 4 倍（校正比值比 4.032[1.031-12.639，=0.045]）。有凸轮形态的人出现放射影像学 OA 特征的患病率为 4-13%，而无凸轮形态的人患病率为 0-3%。与无凸轮形态的人相比，有凸轮形态的人髋关节屈伸和旋转范围较小（=0.018-0.036）。超声特征与患者报告的结果和凸轮形态之间无关联。
在 40-55 岁的队列中，凸轮形态的患病率较高（42%），凸轮形态与髋关节 OA 的放射影像学测量值之间存在显著关系。进一步的纵向研究应探讨年轻人中凸轮形态与髋关节 OA 之间的关系。
