Department of Surgery, University of Nebraska Medical Center, Omaha, USA.
Curr Opin Endocrinol Diabetes Obes. 2020 Oct;27(5):351-357. doi: 10.1097/MED.0000000000000559.
The purpose of this review is to describe the contemporary evaluation and management of tall cell variant of papillary thyroid carcinoma with an emphasis on the clinical features.
Tall cell variant of papillary thyroid carcinoma is the most common aggressive subtype. Within the last few years, the diagnostic criteria for this entity have evolved. Studies have elucidated a better understanding of the clinical implications and pathophysiology of this variant. In this review, the studies presented reflect cumulative and aggregated data from metaanalyses, systematic reviews, and large database investigations utilizing the current diagnostic criteria.
Overall, tall cell variant of papillary thyroid carcinoma represents an aggressive subtype of well-differentiated thyroid carcinoma with more prevalent high-risk features and a poorer clinical outcome.
本文旨在描述高细胞型甲状腺乳头状癌的当代评估和管理，重点介绍其临床特征。
高细胞型甲状腺乳头状癌是最常见的侵袭性亚型。在过去几年中，该实体的诊断标准已经发展。研究阐明了对该变体的临床意义和病理生理学的更好理解。在本综述中，呈现的研究反映了荟萃分析、系统评价和利用当前诊断标准的大型数据库调查的累积和综合数据。
总的来说，高细胞型甲状腺乳头状癌是一种侵袭性的分化型甲状腺癌亚型，具有更普遍的高危特征和更差的临床结局。
