前额皮质在慢性疼痛中的分子、回路和解剖变化。
Molecular, circuit, and anatomical changes in the prefrontal cortex in chronic pain.
机构信息
Department of Neuroscience, University of Texas at Dallas, School of Behavioral and Brain Sciences, Center for Advanced Pain Studies, Richardson, TX, United States.
出版信息
Pain. 2020 Aug;161(8):1726-1729. doi: 10.1097/j.pain.0000000000001897. Epub 2020 Apr 21.
Abstract
The prefrontal cortex undergoes functional and structural reorganization in chronic pain conditions in both rodents and humans. We provide an illustrated overview of the molecular, functional, and connectivity pathology occurring in the prefrontal cortex in chronic pain states.
摘要
前额皮质在啮齿动物和人类的慢性疼痛状态中经历功能和结构的重组。我们提供了一个关于前额皮质在慢性疼痛状态中发生的分子、功能和连接病理学的图示概述。
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