Universidade Federal de Sao Joao Del-Rei, Divinopolis, 35501-296, MG, Brazil.
Universidade de Brasilia, Brasilia, 70910-900, DF, Brazil.
Recent Pat Biotechnol. 2020;14(4):251-268. doi: 10.2174/1872208314666200722160452.
Alpha-amylases are enzymes capable of degrading polysaccharides, such as starch and glycogen. Found in various organisms, such as fungi and bacteria, these enzymes have great biotechnological potential due to their insertion in several industrial sectors ranging from food to biofuels.
The aim of this study was to analyze patents deposited in intellectual property databases on alpha-amylases in the fields of food, beverages, detergents, animal feeds, biofuels, pharmaceuticals and textiles, with the search period being 5 years.
This study targeted the use of alpha-amylases in various industrial sectors, so searches were carried out on the intellectual property database Espacenet website (European Patent Office - EPO) which contains more than 90 million patents deposited in its database.
During the search for patents filed in the last 5 years, 186 were found related to the use of alpha-amylases. These were disturbed as follows: 84 (biofuel), 41 (drinks), 16 (pharmaceuticals), 15 (detergents), 11 (food), 10 (animal feed), 9 (textiles). From the total number of patents found, we selected 6 from each area, except pharmaceutical products, to discuss and provide information on the application of this enzyme.
This study demonstrated that the sectors of beverages and animal feed have preferences for thermostable alpha-amylases while sectors such as food, biofuels and textiles only regarded the importance of enzymatic efficiency. The detergent sector presented the greatest use of alpha-amylases which had distinct biochemical characteristics as solvent resistance and thermostability. The pharmaceutical sector was the one that presented less patents related to the application of alpha amylases. In addition, this work showed that China is the country with the highest patent registration for the use of alpha-amylases in the analyzed period.
α-淀粉酶是能够降解多糖的酶,如淀粉和糖原。这些酶存在于真菌和细菌等各种生物体中,由于它们插入了从食品到生物燃料等多个工业领域,因此具有巨大的生物技术潜力。
本研究旨在分析知识产权数据库中关于食品、饮料、洗涤剂、动物饲料、生物燃料、制药和纺织品领域的α-淀粉酶专利,检索期为 5 年。
本研究针对α-淀粉酶在各个工业领域的应用,因此在知识产权数据库 Espacenet 网站(欧洲专利局-EPO)上进行了搜索,该网站包含其数据库中超过 9000 万项专利。
在搜索过去 5 年内提交的专利时,发现了 186 项与α-淀粉酶的用途有关的专利。这些专利分为以下几类:84 项(生物燃料)、41 项(饮料)、16 项(制药)、15 项(洗涤剂)、11 项(食品)、10 项(动物饲料)、9 项(纺织品)。在所发现的专利总数中,我们从每个领域各选择了 6 个专利进行讨论,并提供有关该酶应用的信息。
本研究表明,饮料和动物饲料行业更喜欢使用热稳定的α-淀粉酶,而食品、生物燃料和纺织品等行业则只重视酶的效率。洗涤剂行业对具有独特生化特性的α-淀粉酶的使用最为广泛,如耐溶剂性和热稳定性。制药行业与α-淀粉酶应用相关的专利较少。此外,这项工作表明,在分析期间,中国是α-淀粉酶专利注册数量最多的国家。