Département de Rhumatologie, Université Cote d'Azur, CHU de Nice, Nice, France.
Laboratoire de Bactériologie, Hôpital L'archet 2, CHU de Nice, Nice, France.
BMC Infect Dis. 2020 Jul 23;20(1):539. doi: 10.1186/s12879-020-05263-5.
Staphylococcus saccharolyticus is a rarely encountered coagulase-negative, which grows slowly and its strictly anaerobic staphylococcus from the skin. It is usually considered a contaminant, but some rare reports have described deep-seated infections. Virulence factors remain poorly known, although, genomic analysis highlights pathogenic potential.
We report a case of Staphylococcus saccharolyticus spondylodiscitis that followed kyphoplasty, a procedure associated with a low rate but possible severe infectious complication (0.46%), and have reviewed the literature. This case specifically stresses the risk of healthcare-associated S. saccharolyticus infection in high-risk patients (those with a history of alcoholism and heavy smoking).
S. saccharolyticus infection is difficult to diagnose due to microbiological characteristics of this bacterium; it requires timely treatment, and improved infection control procedure should be encouraged for high-risk patients.
解糖葡萄球菌是一种罕见的凝固酶阴性、生长缓慢的严格厌氧菌,来自皮肤。它通常被认为是一种污染物,但一些罕见的报告描述了深部感染。毒力因子仍然知之甚少,尽管基因组分析突出了其致病潜力。
我们报告了一例解糖葡萄球菌性脊椎炎病例,该病例继发于椎体后凸成形术,这是一种与低但可能严重的感染并发症(0.46%)相关的手术,我们还回顾了文献。该病例特别强调了在高危患者(有酗酒和大量吸烟史的患者)中与医疗保健相关的解糖葡萄球菌感染的风险。
由于该细菌的微生物学特征,解糖葡萄球菌感染的诊断较为困难;它需要及时治疗,应鼓励对高危患者采取更好的感染控制措施。