Department of Otorhinolaryngology, Maxillofacial and Thyroid Surgery, Fondazione IRCCS, National Cancer Institute of Milan, Milan, Italy.
IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Eur Arch Otorhinolaryngol. 2021 Jan;278(1):149-158. doi: 10.1007/s00405-020-06210-5. Epub 2020 Jul 23.
Management of benign laryngeal stenosis (BLS) remains challenging even though transoral treatments in selected cases have shown satisfactory results, at least comparable to open-neck approaches, with reduced invasiveness. To date, no overall consensus has been reached on many issues. The aim of this study is to assess the effectiveness of a purely transoral treatment in a cohort of patients affected by BLS.
We evaluated 40 patients affected by BLS, treated by transoral surgery between 2013 and 2017. The European Laryngological Society classification for laryngotracheal stenosis was applied for the staging. Improvement in airway patency and quality of life was assessed by decannulation rate, Airway-Dyspnea-Voice-Swallowing (ADVS) score, Voice handicap index (VHI)-30, and Eating assessment tool (EAT)-10 questionnaires.
Mean age was 61 years and M:F ratio was 1.4:1. Previous laryngeal surgery was the most common cause of stenosis (50%), followed by radiotherapy (20%), idiopathic etiology (12%), granulomatosis with polyangiitis (10%), and prolonged intubation (8%). Transoral treatment entailed an improvement in quality of life with a significant decrease in the VHI score (p < 0.0001) and improvement in Airway (p = 0.008), Dyspnea (p < 0.0001), and Voice (p < 0.0001) scores. No major perioperative complications were observed. The decannulation rate among patients with a tracheostomy in place (N = 16) was 63%.
Transoral treatment of selected BLS managed by a team with high-level expertise in surgery and anesthesiology is associated with significant improvement of quality of life, especially with regard to voice and breathing functions.
即使在某些情况下经口治疗显示出令人满意的结果,至少与开放颈部方法相当,且具有较低的侵袭性,良性喉狭窄(BLS)的管理仍然具有挑战性。迄今为止,在许多问题上尚未达成总体共识。本研究的目的是评估一组患有 BLS 的患者接受单纯经口治疗的效果。
我们评估了 2013 年至 2017 年间接受经口手术治疗的 40 例 BLS 患者。应用欧洲喉科学会喉气管狭窄分类对分期进行评估。通过拔管率、气道呼吸困难-声音-吞咽(ADVS)评分、嗓音障碍指数(VHI)-30 评分和饮食评估工具(EAT)-10 问卷评估气道通畅度和生活质量的改善。
平均年龄为 61 岁,男女比例为 1.4:1。以前的喉部手术是最常见的狭窄原因(50%),其次是放疗(20%)、特发性病因(12%)、肉芽肿性多血管炎(10%)和长时间插管(8%)。经口治疗可提高生活质量,VHI 评分显著降低(p<0.0001),气道(p=0.008)、呼吸困难(p<0.0001)和声音(p<0.0001)评分均有所改善。未观察到主要围手术期并发症。有气管造口术的患者(N=16)的拔管率为 63%。
由具有手术和麻醉专业知识的高水平团队对选定的 BLS 进行经口治疗,与生活质量的显著改善相关,特别是在声音和呼吸功能方面。