Team of Ethnopharmacology and Pharmacognosy, Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes, Errachidia, Morocco.
Clin Exp Hypertens. 2021 Jan 2;43(1):49-55. doi: 10.1080/10641963.2020.1797087. Epub 2020 Jul 24.
Lichens are a symbiotic association of a fungus with a green alga or cyanobacterium. They are widely used in traditional medicine as a treatment against skin disorders, diabetes and hypertension.
The goal of this paper was to assess the possible antihypertensive and vasorelaxant capacity of the aqueous extract of a lichen species called Oakmoss or (L.).
In the present study, the aqueous extract of Oakmoss was prepared, its antihypertensive activity was examined in N(ω)-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats, and its vasorelaxant ability was performed in rat isolated thoracic aorta.
The results proved that Oakmoss reduced the systolic, diastolic, mean arterial blood pressure, and heart rate in hypertensive rats but not in normotensive rats. Besides, the data showed that Oakmoss exerts its antihypertensive effect through vasorelaxant ability.
The present study presents the favorable action of Oakmoss as an antihypertensive agent.
地衣是真菌与绿藻或蓝细菌共生的一种共生体。它们在传统医学中被广泛用作治疗皮肤疾病、糖尿病和高血压的药物。
本文旨在评估一种名为橡苔或（L.）的地衣物种的水提物的潜在降压和血管舒张作用。
在本研究中，制备了橡苔的水提物，在 N(ω)-硝基-L-精氨酸甲酯（L-NAME）诱导的高血压大鼠中检测其降压活性，并在大鼠离体胸主动脉中检测其血管舒张能力。
结果证明，橡苔降低了高血压大鼠的收缩压、舒张压、平均动脉压和心率，但对正常血压大鼠没有作用。此外，数据表明，橡苔通过血管舒张能力发挥其降压作用。
本研究表明橡苔具有作为降压药物的有利作用。
