Anestopoulos Ioannis, Kiousi Despoina Eugenia, Klavaris Ariel, Galanis Alex, Salek Karina, Euston Stephen R, Pappa Aglaia, Panayiotidis Mihalis I
Department of Molecular Biology & Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Department of Biological Sciences, University of Cyprus, 2109 Nicosia, Cyprus.
Pharmaceutics. 2020 Jul 21;12(7):688. doi: 10.3390/pharmaceutics12070688.
Surface active agents (SAAs) are molecules with the capacity to adsorb to solid surfaces and/or fluid interfaces, a property that allows them to act as multifunctional ingredients (e.g., wetting and dispersion agents, emulsifiers, foaming and anti-foaming agents, lubricants, etc.) in a widerange of the consumer products of various industrial sectors (e.g., pharmaceuticals, cosmetics, personal care, detergents, food, etc.). Given their widespread utilization, there is a continuously growing interest to explore their role in consumer products (relevant to promoting human health) and how such information can be utilized in order to synthesize better chemical derivatives. In this review article, weaimed to provide updated information on synthetic and biological (biosurfactants) SAAs and their health-promoting properties (e.g., anti-microbial, anti-oxidant, anti-viral, anti-inflammatory, anti-cancer and anti-aging) in an attempt to better define some of the underlying mechanism(s) by which they exert such properties.
表面活性剂(SAAs)是一类能够吸附于固体表面和/或流体界面的分子,这一特性使它们能够在各工业领域的多种消费品(如药品、化妆品、个人护理产品、洗涤剂、食品等)中作为多功能成分(如润湿剂、分散剂、乳化剂、发泡剂和消泡剂、润滑剂等)发挥作用。鉴于其广泛应用,人们对探索它们在消费品(与促进人类健康相关)中的作用以及如何利用这些信息来合成更好的化学衍生物的兴趣与日俱增。在这篇综述文章中,我们旨在提供有关合成表面活性剂和生物表面活性剂(生物表面活性剂)及其促进健康特性(如抗菌、抗氧化、抗病毒、抗炎、抗癌和抗衰老)的最新信息,以便更好地确定它们发挥这些特性的一些潜在机制。