Deguelte Sophie, Perrier Marine, Hammoutene Cheryne, Cadiot Guillaume, Kianmanesh Reza
Digestive Surgery Department, Reims University Hospital, Robert Debré Hospital, F-51092 Reims, France.
Clinical Research Department, Reims University Hospital, Robert Debré Hospital, F-51092 Reims, France.
J Clin Med. 2020 Jul 21;9(7):2319. doi: 10.3390/jcm9072319.
Small-intestinal neuroendocrine tumors (SI-NETs) are the most prevalent small bowel neoplasms with an increasing frequency. In the multimodal management of SI-NETs, surgery plays a key role, either in curative intent, even if R0 resection is feasible in only 20% of patients due to advanced stage at diagnosis, or palliative intent. Surgeons must be informed about the specific surgical management of SI-NETs according to their hormonal secretion, their usual dissemination at the time of diagnosis and the need for bowel-preserving surgery to avoid short bowel syndrome. The aim of this paper is to review the surgical indications and techniques, and perioperative and postoperative management of SI-NETs.
小肠神经内分泌肿瘤（SI-NETs）是最常见的小肠肿瘤，其发病率呈上升趋势。在SI-NETs的多模式管理中，手术起着关键作用，无论是出于根治目的（尽管由于诊断时处于晚期，仅20%的患者可行R0切除）还是姑息目的。外科医生必须了解SI-NETs根据其激素分泌、诊断时常见的播散情况以及避免短肠综合征所需的保肠手术的具体手术管理方法。本文旨在综述SI-NETs的手术适应证、技术以及围手术期和术后管理。
