Servicio de Investigación Clínica, Hospital Infantil de México Federico Gómez, Ciudad de México, México.
Departamento de Neonatología, Hospital Infantil de México Federico Gómez, Ciudad de México, México.
Bol Med Hosp Infant Mex. 2020;77(4):202-206. doi: 10.24875/BMHIM.20000041.
Pulmonary arterial hypertension is a multifactorial nosological entity that increases neonatal mortality as a result of heart failure. Pulmonary vasodilators are the cornerstone of treatment, of which sildenafil is the most commonly used drug. Therefore, the results of a recently updated Cochrane systematic review are summarized, in which the efficacy and safety of sildenafil for the treatment of pulmonary hypertension in neonates was evaluated.
肺动脉高压是一种多因素的疾病实体，可导致心力衰竭而使新生儿死亡率增加。肺血管扩张剂是治疗的基石，其中西地那非是最常用的药物。因此，总结了最近更新的 Cochrane 系统评价的结果，该评价评估了西地那非治疗新生儿肺动脉高压的疗效和安全性。
