双侧高频重复经颅磁刺激对精神分裂症认知功能的影响。
The effect of bilateral high frequency repetitive transcranial magnetic stimulation on cognitive functions in schizophrenia.
作者信息
Güleken Mehmet Diyaddin, Akbaş Taner, Erden Selime Çelik, Akansel Veysel, Al Zeliha Cengiz, Özer Ömer Akil
机构信息
Department of Psychiatry, Gazi Yaşargil Training and Research Hospital, Sağlık Bilimleri Üniversitesi, Diyarbakır, Turkey.
Department of Psychiatry, Şişli Hamidiye Etfal Training and Research Hospital, Sağlık Bilimleri Üniversitesi, İstanbul, Turkey.
出版信息
Schizophr Res Cogn. 2020 Jul 16;22:100183. doi: 10.1016/j.scog.2020.100183. eCollection 2020 Dec.
•Despite their major effects on positive symptoms, antipsychotics do not have a significant effect on cognition in schizophrenia•Bilateral high frequency rTMS targeting dorsolateral prefrontal cortices has been effective on working memory•Bilateral 20 Hz rTMS improved attention and verbal working memory in schizophrenia patients,•It also improved the competence of switching the perceptional set up under a disruptive effect towards new instructions, in this study.
•尽管抗精神病药物对阳性症状有主要影响，但对精神分裂症的认知没有显著影响。
•针对双侧背外侧前额叶皮层的高频重复经颅磁刺激（rTMS）对工作记忆有效。
•双侧20赫兹rTMS改善了精神分裂症患者的注意力和言语工作记忆。
•在本研究中，它还提高了在对新指令的干扰作用下切换感知设定的能力。
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