Madsen T, Erlangsen A, Hjorthøj C, Nordentoft M
Danish Research Institute for Suicide Prevention, Mental Health Centre Copenhagen, Copenhagen, Denmark.
CORE-Copenhagen Research Center for Mental Health Mental Health Centre Copenhagen, Copenhagen, Denmark.
Acta Psychiatr Scand. 2020 Nov;142(5):355-365. doi: 10.1111/acps.13221. Epub 2020 Aug 27.
Over recent decades, intense efforts to address suicides in psychiatric admitted people have been initiated. The aim was to calculate suicide rates, rate ratios, population attributable risks (PAR) and trends among people admitted to or recently discharged from psychiatric wards.
Using a cohort design, we obtained nationwide register data on 6 292 932 individuals aged 15+ living in Denmark during 1995-2016. Of these, 178 703 (5.73%) males and 201 033 females (6.33%) had been admitted to psychiatric hospital. Incidence rate ratios (IRR) were obtained using Poisson regression analyses while adjusting for age and calendar period. Trends were assessed using joinpoint analyses.
In total, 15 075 persons died by suicide, of which 6174 had been psychiatrically admitted. Among males, the suicide rate during the first week of admission and after discharge was 3409 and 3148 per 100 000 person-years, respectively. The corresponding values for females were 1267 and 1631. Generally, estimated suicide rates were highest in those with affective or anxiety stress disorders. During first week of hospitalization, the IRR was 237 for males and of 322 for females when compared with those never hospitalized. In first week after discharge, the IRR was 225 and 425 for males and females, respectively. PAR estimates indicated 6% of male suicides and 13% of female suicides attributes to first week of admission and discharge. The inpatient suicide rate decreased annually 2.5% until 2009 followed by a 7.5% annual percentage increase. The suicide rate after discharge decreased steadily annually over the study period.
Despite finding declining post-discharge suicide rates, the period surrounding a psychiatric admission was still associated with extremely high suicide rates.
在最近几十年里,人们已经开始为解决精神病住院患者的自杀问题付出巨大努力。目的是计算自杀率、率比、人群归因风险(PAR)以及精神病病房收治或近期出院患者中的自杀趋势。
采用队列设计,我们获取了1995年至2016年期间丹麦全国范围内6292932名15岁及以上居民的登记数据。其中,178703名男性(5.73%)和201033名女性(6.33%)曾入住精神病院。发病率比(IRR)通过泊松回归分析得出,同时对年龄和日历时间进行了调整。趋势通过连接点分析进行评估。
总共有15075人死于自杀,其中6174人曾入住精神病院。在男性中,入院第一周和出院后的自杀率分别为每10万人年3409例和3148例。女性的相应数值为1267例和1631例。一般来说,估计自杀率在患有情感或焦虑应激障碍的人群中最高。在住院第一周,与从未住院的人相比,男性的IRR为237,女性为322。在出院后的第一周,男性和女性的IRR分别为225和425。PAR估计表明,6%的男性自杀和13%的女性自杀归因于入院和出院的第一周。住院患者自杀率在2009年之前每年下降2.5%,之后每年上升7.5%。在研究期间,出院后的自杀率每年稳步下降。
尽管发现出院后自杀率有所下降,但精神病入院前后这段时间仍与极高的自杀率相关。