Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Ann Surg Oncol. 2020 Oct;27(10):3672-3682. doi: 10.1245/s10434-020-08872-1. Epub 2020 Jul 27.
Multimodality treatment of primary soft tissue sarcoma has evolved over the last 50 years, including seminal studies in amputation versus limb-sparing surgery, incorporation of radiation therapy (XRT), and the continuing controversy over the utilization and efficacy of systemic chemotherapy. We review the landmark studies in the multimodality management of primary extremity and trunk soft tissue sarcoma.
过去 50 年来,原发性软组织肉瘤的多模态治疗不断发展,包括在截肢与保肢手术、放射治疗(XRT)的应用、以及系统化疗的应用和疗效方面的持续争议等方面的开创性研究。我们回顾了原发性肢体和躯干软组织肉瘤多模态治疗中的标志性研究。