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肝硬化伴门静脉高压患者的减重手术:高危患者 Roux-en-Y 胃旁路手术的构建与特殊性

Bariatric Surgery in the Setting of Liver Cirrhosis with Portal Hypertension: the Confection and Particularities of Roux-en-Y Gastric Bypass in a High-Risk Patient.

作者信息

Frey Sebastien, Petrucciani Niccolo, Iannelli Antonio

机构信息

Université Côte d'Azur, Nice, France.

Digestive Surgery and Liver Transplantation Unit, Centre Hospitalier Universitaire de Nice, Archet 2 Hospital, Nice, France.

出版信息

Obes Surg. 2020 Oct;30(10):4165-4166. doi: 10.1007/s11695-020-04715-w. Epub 2020 Jul 27.

Abstract

INTRODUCTION

Morbid obesity is associated with the occurrence of non-alcoholic fatty liver disease, which may progress to cirrhosis. Although weight loss is the treatment of choice, surgical management can be challenging at the stage of cirrhosis. The aim of this video report is to present the confection and the features of a Roux-en-Y gastric bypass (RYGB) in the setting of liver cirrhosis.

METHODS

We present the case of a 60-year-old man with a weight of 115 kg and a corresponding BMI of 38.9 kg/m, with non-alcoholic steatohepatitis (NASH)-related liver cirrhosis. The latter was compensated (Child-Turcott-Pugh score at A6) but the patient had already undergone three esophageal variceal ligations. Portal hypertension with splenomegaly was clearly visible on preoperative workup.

RESULTS

In this video, we show how to perform RYGB in a case of liver cirrhosis, with a focus on common pitfalls. The main risks remain perioperative bleeding due to portal hypertension and impaired coagulation, as well as the decompensation of the cirrhosis. A careful preoperative nutritional and hepatological evaluation is mandatory since the perioperative risk of morbidities is higher.

CONCLUSION

RYGB is a feasible option in selected patients with morbid obesity and cirrhosis. These patients ideally should be managed in centers having experience in bariatric surgery and hepatology.

摘要

引言

病态肥胖与非酒精性脂肪性肝病的发生有关,后者可能进展为肝硬化。尽管减肥是首选治疗方法,但在肝硬化阶段进行手术治疗可能具有挑战性。本视频报告的目的是介绍肝硬化患者 Roux-en-Y 胃旁路术(RYGB)的操作过程及特点。

方法

我们报告一例 60 岁男性患者,体重 115 千克,体重指数(BMI)为 38.9kg/m²,患有非酒精性脂肪性肝炎(NASH)相关肝硬化。该患者肝硬化处于代偿期(Child-Turcott-Pugh 评分 A6 级),但已接受过三次食管静脉曲张结扎术。术前检查清晰显示门静脉高压伴脾肿大。

结果

在本视频中,我们展示了如何在肝硬化患者中实施 RYGB,重点关注常见的陷阱。主要风险仍然是门静脉高压和凝血功能受损导致的围手术期出血,以及肝硬化失代偿。由于围手术期发病风险较高,术前进行仔细的营养和肝脏评估是必不可少的。

结论

RYGB 对于选定的病态肥胖和肝硬化患者是一种可行的选择。这些患者理想情况下应在有减肥手术和肝病治疗经验的中心接受治疗。

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