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Spelunking in Sputum: Single-Cell RNA Sequencing Sheds New Insights into Cystic Fibrosis.

作者信息

Iwanaga Naoki, Kolls Jay K

机构信息

Center for Translational Research in Infection and Inflammation Tulane University School of Medicine New Orleans, Louisiana.

出版信息

Am J Respir Crit Care Med. 2020 Nov 15;202(10):1336-1337. doi: 10.1164/rccm.202006-2456ED.

DOI:10.1164/rccm.202006-2456ED
PMID:32721178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7667890/
Abstract
摘要

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本文引用的文献

1
Single-Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis.囊性纤维化气道炎症的单细胞转录表型。
Am J Respir Crit Care Med. 2020 Nov 15;202(10):1419-1429. doi: 10.1164/rccm.202004-0991OC.
2
Single-Cell Flow Cytometry Profiling of BAL in Children.儿童支气管肺泡灌洗液的单细胞流式细胞仪分析。
Am J Respir Cell Mol Biol. 2020 Aug;63(2):152-159. doi: 10.1165/rcmb.2019-0453MA.
3
Pseudomonas aeruginosa antibody response in cystic fibrosis decreases rapidly following lung transplantation.铜绿假单胞菌抗体反应在肺移植后迅速减少在囊性纤维化。
J Cyst Fibros. 2020 Jul;19(4):587-594. doi: 10.1016/j.jcf.2020.01.012. Epub 2020 Feb 8.
4
Using single-cell RNA sequencing to unravel cell lineage relationships in the respiratory tract.利用单细胞 RNA 测序揭示呼吸道中的细胞谱系关系。
Biochem Soc Trans. 2020 Feb 28;48(1):327-336. doi: 10.1042/BST20191010.
5
Targeting Proteases in Cystic Fibrosis Lung Disease. Paradigms, Progress, and Potential.针对囊性纤维化肺部疾病中的蛋白酶。范例、进展与潜力。
Am J Respir Crit Care Med. 2020 Jan 15;201(2):141-147. doi: 10.1164/rccm.201906-1190PP.
6
Niches for the Long-Term Maintenance of Tissue-Resident Memory T Cells.组织驻留记忆 T 细胞的长期维持龛位。
Front Immunol. 2018 May 31;9:1214. doi: 10.3389/fimmu.2018.01214. eCollection 2018.
7
Frontline Science: Pathological conditioning of human neutrophils recruited to the airway milieu in cystic fibrosis.前沿科学：囊性纤维化气道环境中募集的人中性粒细胞的病理条件作用。
J Leukoc Biol. 2018 Oct;104(4):665-675. doi: 10.1002/JLB.5HI1117-454RR. Epub 2018 May 9.
8
Transcriptomic profile of cystic fibrosis patients identifies type I interferon response and ribosomal stalk proteins as potential modifiers of disease severity.囊性纤维化患者的转录组图谱确定I型干扰素反应和核糖体柄蛋白是疾病严重程度的潜在调节因子。
PLoS One. 2017 Aug 28;12(8):e0183526. doi: 10.1371/journal.pone.0183526. eCollection 2017.
9
IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae.肺上皮细胞中的白细胞介素-17受体信号传导对于粘膜趋化因子梯度以及肺部抵御肺炎克雷伯菌的宿主防御是必需的。
Cell Host Microbe. 2016 Nov 9;20(5):596-605. doi: 10.1016/j.chom.2016.10.003. Epub 2016 Oct 27.
10
Cystic fibrosis.囊性纤维化。
Lancet. 2016 Nov 19;388(10059):2519-2531. doi: 10.1016/S0140-6736(16)00576-6. Epub 2016 Apr 29.