Deville C, Roques X, Fernandez G, Laborde N, Baudet E, Fontan F
Hôpital Cardiologique du Haut-Leveque, Pessac-Bordeaux, France.
Eur J Cardiothorac Surg. 1988;2(3):185-91. doi: 10.1016/1010-7940(88)90069-3.
Our experience (January 1982-May 1987) concerns 41 patients, operated upon for aortic dissection (30 patients) or aneurysm (11 patients) using circulatory arrest with deep hypothermia. There were 24 male and 17 female patients (mean age: 55 years 9 months, range 32-73 years). The mean circulatory arrest time in minutes was 41 +/- 3 (mean rectal temperature before circulatory arrest was 18.4 degrees C +/- 0.3 degrees C). Total (24 patients) or partial (16 patients) replacement of the aortic arch was performed. One patient with a sacciform aneurysm had the aortic wall defect closed. Hospital mortality was 22% +/- 7% (9 patients): 8 of 30 patients with aortic dissection (26.6%) and 1 of 11 patients with aortic aneurysm (9%). Neurological complications occurred in 3 patients. These data lead us to prefer circulatory arrest with deep hypothermia as the method of choice for aortic arch surgery. However, when a short circulatory arrest time (less than 30 min) for the repair is foreseeable, mild hypothermia (20 degrees C-24 degrees C) may be preferred. In patients who will not tolerate excessive cardiopulmonary bypass times, expected difficulties with the repair should suggest mild hypothermia and short circulatory arrest in easier cases or moderate hypothermia with brachiocephalic perfusion in the others.
我们的经验(1982年1月至1987年5月)涉及41例患者,这些患者因主动脉夹层(30例)或动脉瘤(11例)接受了深低温循环停止手术。其中男性患者24例,女性患者17例(平均年龄:55岁9个月,范围32 - 73岁)。平均循环停止时间为41±3分钟(循环停止前平均直肠温度为18.4℃±0.3℃)。进行了全主动脉弓置换(24例)或部分主动脉弓置换(16例)。1例囊状动脉瘤患者的主动脉壁缺损得到闭合。医院死亡率为22%±7%(9例):30例主动脉夹层患者中有8例(26.6%),11例主动脉瘤患者中有1例(9%)。3例患者出现神经并发症。这些数据使我们倾向于选择深低温循环停止作为主动脉弓手术的首选方法。然而,当预计修复所需的循环停止时间较短(少于30分钟)时,可能更倾向于轻度低温(20℃ - 24℃)。对于不能耐受过长体外循环时间的患者,若预计修复有困难,在较简单的病例中应选择轻度低温和短循环停止,其他病例则应选择中度低温并进行头臂灌注。