Suppr超能文献

调节口腔微生物群作为治疗内分泌、代谢和免疫紊乱的有效工具。

Rebalancing the Oral Microbiota as an Efficient Tool in Endocrine, Metabolic and Immune Disorders.

作者信息

Isacco Ciro Gargiulo, Ballini Andrea, De Vito Danila, Nguyen Kieu Cao Diem, Cantore Stefania, Bottalico Lucrezia, Quagliuolo Lucio, Boccellino Mariarosaria, Di Domenico Marina, Santacroce Luigi, Arrigoni Roberto, Dipalma Gianna, Inchingolo Francesco

机构信息

Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70121 Bari, Italy.

Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80100 Naples, Italy.

出版信息

Endocr Metab Immune Disord Drug Targets. 2021;21(5):777-784. doi: 10.2174/1871530320666200729142504.

Abstract

The current treatment and prevention procedures of oral disorders follow a very targeted approach considering mouth and its structures as a system that is completely independent, than the rest of the body. The main therapeutic approach is to keep the levels of oral bacteria and hygiene in an acceptable range compatible with oral-mouth health, completely separated from systemic microbial homeostasis (eubiosis vs dysbiosis). This can negatively impact the diagnosis of a more complex systemic disease and its progression. Dysbiosis occurs as a consequence of imbalance in oral and gut microbiota which leads to cardiovascular diseases, diabetes mellitus, rheumatoid arthritis, and Alzheimer's disease, as reported in current literature. Likewise, there is a need to highlight and develop a novel philosophical approach in the treatments for oral diseases that will necessarily involve nonconventional approaches.

摘要

目前口腔疾病的治疗和预防程序采用的是一种非常有针对性的方法,将口腔及其结构视为一个完全独立于身体其他部分的系统。主要的治疗方法是将口腔细菌水平和口腔卫生保持在与口腔健康相容的可接受范围内,与全身微生物稳态(正常微生物群与失调微生物群)完全分开。这可能会对更复杂的全身性疾病的诊断及其进展产生负面影响。正如当前文献所报道的,失调微生物群是口腔和肠道微生物群失衡的结果,会导致心血管疾病、糖尿病、类风湿性关节炎和阿尔茨海默病。同样,有必要突出并开发一种新的口腔疾病治疗哲学方法,这种方法必然会涉及非传统方法。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验