Valente M, Bortolotti U, Thiene G, Arbustini E, Milano A, Mazzucco A, Gallucci V
Department of Pathology, University of Padova, Medical School, Italy.
Eur J Cardiothorac Surg. 1987;1(3):134-8. doi: 10.1016/1010-7940(87)90028-5.
The occurrence of stent post deformity was investigated in 38 consecutive, polypropylene flexible-stented Hancock porcine bioprostheses (PB) recovered from the mitral position because of early postoperative death or late tissue failure. The degree of deformity was assessed for each explant by calculating the triangular area obtained by projecting the apex of the stent posts on a plane and comparing it with the same area calculated for unimplanted PBs of comparable size. A significant stent deformity (reduction of the triangular area greater than 40%) was observed only in 6 PBs explanted because of tissue failure after a mean function time of 69.6 +/- 28 months. In these PBs, scanning electron microscopy of the bare surface of the stent at the point of maximal flexion showed cracks 0.7-1 microns large, which represent the morphological substrate of the so-called "creep" of polypropylene. Inward stent post bending may occur after implantation in mitral PBs and when severe, it corresponds to a definite ultrastructural plastic deformity of polypropylene.
对38个连续的、因术后早期死亡或晚期组织衰竭而从二尖瓣位置取出的聚丙烯柔性支架汉考克猪生物瓣膜(PB)进行了支架柱后畸形发生情况的研究。通过计算将支架柱顶端投影到一个平面上所得到的三角形面积,并将其与为大小相当的未植入PB计算的相同面积进行比较,来评估每个外植体的畸形程度。仅在平均功能时间为69.6±28个月后因组织衰竭而取出的6个PB中观察到显著的支架畸形(三角形面积减少大于40%)。在这些PB中,对支架最大弯曲点处裸露表面的扫描电子显微镜检查显示有0.7 - 1微米大的裂缝,这代表了聚丙烯所谓“蠕变”的形态学基础。二尖瓣PB植入后可能会发生支架柱向内弯曲,严重时,这对应于聚丙烯明确的超微结构塑性变形。