用振摇生理盐水对比来描绘新生儿中心静脉导管的位置。
Agitated saline contrast to delineate central venous catheter position in neonates.
机构信息
Department of Neonatology, All India Institute of Medical Sciences, Rishikesh, India.
Division of Cardiology, Department of Pediatrics, All India Institute of Medical Sciences, Rishikesh, India.
出版信息
J Perinatol. 2021 Jul;41(7):1638-1644. doi: 10.1038/s41372-020-0761-7. Epub 2020 Jul 29.
OBJECTIVE
Central venous catheter (CVC) insertion is required for the management of sick neonates. Ultrasonography/targeted neonatal echocardiography (TNE) with/without normal saline (NS) flush is used to identify CVC position. The present study compared the visibility and safety of agitated saline (AS) with normal saline (NS) flush.
STUDY DESIGN
This prospective interventional study included 110 CVC insertions, both umbilical venous catheterization (UVC) and peripherally inserted central catheterization (PICC). Catheter position was monitored by real-time TNE.
RESULTS
Overall visibility of catheter tip (combined UVC and PICC) was significantly better in AS (n = 55) compared with NS group (n = 55) [48/55 (87.2%) vs. 28/55 (50.9%); p < 0.0001]. Time to detect catheter tip by AS push was significantly less than that of NS push. There was no difference in the amount of saline flush required with either method. No major adverse effect was observed.
CONCLUSIONS
AS push can be used as a safe method to delineate CVC position in neonates.
目的
对于患病新生儿的治疗，常需要使用中心静脉导管（CVC）。超声/靶向新生儿超声心动图（TNE）联合/不联合生理盐水（NS）冲洗可用于确定 CVC 位置。本研究比较了生理盐水冲洗和生理盐水冲洗的可见度和安全性。
研究设计
这是一项前瞻性介入研究，共纳入 110 例 CVC 插入术，包括脐静脉导管（UVC）和外周插入的中心导管（PICC）。通过实时 TNE 监测导管尖端位置。
结果
与 NS 组（n=55）相比，AS 组（n=55）的导管尖端总体可见度明显更好[48/55（87.2%）比 28/55（50.9%）；p<0.0001]。AS 推注检测到导管尖端的时间明显短于 NS 推注。两种方法所需的冲洗生理盐水量无差异。未观察到主要不良事件。
结论
AS 推注可作为一种安全的方法来描绘新生儿 CVC 位置。
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