Pisano Calogera, Nardi Paolo, Balistreri Carmela Rita, Altieri Claudia, Bertoldo Fabio, Ruvolo Giovanni
Cardiac Surgery Unit, Tor Vergata University Hospital, Rome, Italy.
Department of Pathobiology and Medical and Forensic Biotechnologies, University of Palermo, Palermo, Italy.
Kardiochir Torakochirurgia Pol. 2020 Mar;17(1):1-7. doi: 10.5114/kitp.2020.94183. Epub 2020 Apr 9.
Cardiovascular disease (CVD) presents a great burden for elderly patients, their caregivers, and health systems. Structural and functional alterations of vessels accumulate throughout life, culminating in increased risk of developing CVD. Several inflammatory pathway are involved in vascular ageing. The growing elderly population worldwide highlights the need to understand how aging promotes CVD in order to develop new strategies to confront this challenge. In this review we analyzed the role of stem cells and new intervention measures as emerging drugs for vascular aging.
心血管疾病（CVD）给老年患者、他们的照料者以及卫生系统带来了巨大负担。血管的结构和功能改变在一生中不断累积，最终导致患心血管疾病的风险增加。几条炎症途径参与了血管老化过程。全球老年人口的不断增加凸显了了解衰老如何促进心血管疾病发生以制定应对这一挑战的新策略的必要性。在本综述中，我们分析了干细胞的作用以及作为血管老化新兴药物的新干预措施。
