Khan Dr Adnan, Shaikh Dr Nissar, Khan Dr Mohsin, Alkubaisi Dr Aisha, Al Rumaihi D Ghaya, Al-Sulaiti Dr Ghanem, Ayyad Dr Ali
Department of Neurosurgery: Neuroscience Institute: Hamad Medical Corporation Doha, Qatar.
Surgical intensive care unit: Hamad Medical Corporation Doha, Qatar.
Qatar Med J. 2020 Jul 16;2020(1):19. doi: 10.5339/qmj.2020.19. eCollection 2020.
Spontaneous subarachnoid hemorrhage (SAH) is one of the significant etiologies for stroke. SAH causes higher morbidity and mortality with loss of productivity, resulting in increased disease burden. Only few studies in Qatar have reported on SAH, and the epidemiological features of SAH and aneurysmal SAH (aSAH) have not been comprehensively studied before in Qatar. Our study aimed to describe the epidemiological profile of patients with SAH and aSAH in the State of Qatar.
We reviewed the medical records of all patients with SAH and/or ruptured aneurysm who were consecutively admitted to Hamad General Hospital (600-bed tertiary care facility) from January 1, 2007 to December 31, 2016. We performed a quantitative analysis of demographics, clinical characteristics, diagnostic findings, interventions, and overall mortality. We used SPSS version 18 for data entry. We used chi-square and student t tests to compare the groups. We considered < 0.05 as statistically significant.
The study included 323 patients with aneurysmal and non-aneurysmal SAH. The mean age at presentation was 47.4 ± 12.2 years. Men comprised 68.7% of the cases. Further, 86.6% of the patients presented with acute-onset headache. Additionally, 217 patients had 1 aneurysm, and 32 patients had multiple aneurysms. Anterior communicating artery aneurysm has been found to be the most common aneurysm. Non-aneurysmal SAH occurred in 74 patients (22.9%), with male predominance. Moreover, 23.7% and 52.6% of the patients underwent microsurgical clipping and coiling of the aneurysm, respectively. The overall mortality in World Federation of Neurosurgeon Score (WFNS) grades 1 and 2 SAH was lesser than that in higher grades (28.6% vs 71.4%). Of 323 patients, 69 died within 1 month post-ictus, accounting for an overall mortality rate of 21.2% in our study.
The annual incidence of aneurysmal SAH in Qatar has been increasing. Men had a higher incidence of aSAH. Internal carotid aneurysms have been found to be more common in Qatari women, which may have a genetic basis. Lower WFNS grades of aSAH have been associated with better prognosis. The overall mortality associated with aSAH in Qatar has declined over the last 3 years.
自发性蛛网膜下腔出血（SAH）是中风的重要病因之一。SAH导致更高的发病率和死亡率，造成生产力损失，从而增加疾病负担。卡塔尔仅有少数关于SAH的研究报道，此前卡塔尔尚未对SAH和动脉瘤性SAH（aSAH）的流行病学特征进行全面研究。我们的研究旨在描述卡塔尔国SAH和aSAH患者的流行病学概况。
我们回顾了2007年1月1日至2016年12月31日期间连续入住哈马德总医院（一家拥有600张床位的三级护理机构）的所有SAH和/或破裂动脉瘤患者的病历。我们对人口统计学、临床特征、诊断结果、干预措施和总体死亡率进行了定量分析。我们使用SPSS 18版进行数据录入。我们使用卡方检验和学生t检验来比较各组。我们将P < 0.05视为具有统计学意义。
该研究纳入了323例动脉瘤性和非动脉瘤性SAH患者。就诊时的平均年龄为47.4 ± 12.2岁。男性占病例的68.7%。此外，86.6%的患者表现为急性发作性头痛。另外，217例患者有1个动脉瘤，32例患者有多个动脉瘤。已发现前交通动脉瘤是最常见的动脉瘤。非动脉瘤性SAH发生在74例患者中（22.9%），以男性为主。此外，分别有23.7%和52.6%的患者接受了动脉瘤的显微手术夹闭和血管内栓塞治疗。世界神经外科医师联盟（WFNS）1级和2级SAH的总体死亡率低于较高等级（28.6%对71.4%）。在323例患者中，69例在发病后1个月内死亡，在我们的研究中总体死亡率为21.2%。
卡塔尔动脉瘤性SAH的年发病率一直在上升。男性aSAH的发病率较高。已发现颈内动脉瘤在卡塔尔女性中更为常见，这可能有遗传基础。aSAH的WFNS等级较低与较好的预后相关。在过去3年中，卡塔尔与aSAH相关的总体死亡率有所下降。
