Department of Public Health and Health Education, The College at Brockport, State University of New York, Brockport, NY, 14420, USA.
Department of Applied Heath Science, Indiana University School of Public Health Bloomington, Bloomington, IN, 47405, USA.
J Cancer Educ. 2022 Jun;37(3):508-516. doi: 10.1007/s13187-020-01837-8.
This cross-sectional, secondary data analysis examines the association between cigarette smoking and self-reported health-related quality of life (HRQoL) in adult survivors of Adolescent and Young Adult Cancer. Pooled data for survivors of Adolescent and Young Adult Cancer (N = 1495) were drawn from the 2016 and 2017 Behavioral Risk Factor Surveillance Survey. Binary logistic regression models were utilized to examine independent associations between each of the four HRQoL domains (i.e., self-related general health, activity limitation days, poor physical, and mental health days) and cigarette smoking. Of the 1495 Adolescent and Young Adult Onset Cancer Survivors (AYAO-CS) in this study, approximately 30% reported currently smoking cigarettes. Relative to never smokers, the odds of reporting fair/poor general health were significantly higher for current and former smokers: (OR = 3.95, 95% CI: 2.08-7.50) and (OR = 2.51, 95% CI: 1.46-4.32), respectively. Likewise, current smokers were significantly more likely to report frequent days of poor physical health (OR = 2.79, 95% CI: 1.38-5.65). The study findings suggest a significant cross-sectional association between cigarette smoking and poor health-related quality of life in adult survivors of adolescent and young adult cancer. These findings, although cross-sectional, underscore the need for prospective studies to examine the longitudinal association between HRQoL and cigarette smoking among cancer survivors. Findings also help establish both the need for smoking cessation programs and the importance of effective strategies for addressing HRQoL issues among cancer survivors.
本横断面二次数据分析研究了青少年及青年期癌症成年幸存者中吸烟与自我报告的健康相关生活质量（HRQoL）之间的关系。青少年及青年期癌症幸存者（n=1495）的数据来自于 2016 年和 2017 年的行为风险因素监测调查。采用二元逻辑回归模型，分别检验了四个 HRQoL 领域（即自我相关一般健康、活动受限天数、身体和心理健康不良天数）与吸烟之间的独立关联。在本研究的 1495 名青少年和青年期癌症幸存者（AYAO-CS）中，约 30%的人报告目前吸烟。与从不吸烟者相比，目前吸烟者和曾经吸烟者报告一般健康状况较差的几率明显更高：（OR=3.95，95%CI：2.08-7.50）和（OR=2.51，95%CI：1.46-4.32）。同样，目前吸烟者报告身体状况不佳的天数明显更多（OR=2.79，95%CI：1.38-5.65）。研究结果表明，在青少年和青年期癌症成年幸存者中，吸烟与较差的健康相关生活质量之间存在显著的横断面关联。这些发现虽然是横断面的，但强调了需要进行前瞻性研究，以检查癌症幸存者 HRQoL 和吸烟之间的纵向关联。研究结果还帮助确定了戒烟计划的必要性，以及为癌症幸存者解决 HRQoL 问题的有效策略的重要性。
