The Ohio State University Wexner Medical Center, Neurology department, Columbus, Ohio, USA.
Epileptic Disord. 2020 Aug 1;22(4):511-514. doi: 10.1684/epd.2020.1189.
Epidiolex (cannabidiol, aka CBD) is a recently approved FDA prescription drug for the treatment of epilepsy associated with Lennox-Gastaut and Dravet syndromes, and is increasingly used for treatment-resistant epilepsy. Rash was rarely reported in Epidiolex clinical trial data. We report a case of Epidiolex-related skin rash that developed in a delayed fashion in a 23-year-old female with medically refractory epilepsy. We also review the potential mechanism of Epidiolex-related skin rash.
依庇洛芬（大麻二酚，又名 CBD）是一种最近被美国食品药品监督管理局批准的处方药物，用于治疗与 Lennox-Gastaut 和 Dravet 综合征相关的癫痫，并且越来越多地用于治疗耐药性癫痫。在依庇洛芬的临床试验数据中，皮疹的报告很少见。我们报告了一例 23 岁女性癫痫患者在使用依庇洛芬治疗后出现迟发性皮疹的病例。我们还回顾了依庇洛芬相关皮疹的潜在机制。
