Academic Department of Rehabilitation Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, School of Medicine, University of Leeds, Leeds, UK.
National Demonstration Centre for Rehabilitation Medicine, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
J Med Virol. 2021 Feb;93(2):1013-1022. doi: 10.1002/jmv.26368. Epub 2020 Aug 17.
There is currently very limited information on the nature and prevalence of post-COVID-19 symptoms after hospital discharge.
A purposive sample of 100 survivors discharged from a large University hospital were assessed 4 to 8 weeks after discharge by a multidisciplinary team of rehabilitation professionals using a specialist telephone screening tool designed to capture symptoms and impact on daily life. EQ-5D-5L telephone version was also completed.
Participants were between 29 and 71 days (mean 48 days) postdischarge from hospital. Thirty-two participants required treatment in intensive care unit (ICU group) and 68 were managed in hospital wards without needing ICU care (ward group). New illness-related fatigue was the most common reported symptom by 72% participants in ICU group and 60.3% in ward group. The next most common symptoms were breathlessness (65.6% in ICU group and 42.6% in ward group) and psychological distress (46.9% in ICU group and 23.5% in ward group). There was a clinically significant drop in EQ5D in 68.8% in ICU group and in 45.6% in ward group.
This is the first study from the United Kingdom reporting on postdischarge symptoms. We recommend planning rehabilitation services to manage these symptoms appropriately and maximize the functional return of COVID-19 survivors.
目前关于 COVID-19 出院后症状的性质和流行情况的信息非常有限。
对一家大型大学医院出院的 100 名幸存者进行了有目的的抽样，由康复专业人员组成的多学科团队在出院后 4 至 8 周使用专门的电话筛查工具进行评估，该工具旨在捕捉症状和对日常生活的影响。还完成了 EQ-5D-5L 电话版本。
参与者在出院后 29 至 71 天（平均 48 天）之间。32 名参与者需要在重症监护病房（ICU 组）接受治疗，68 名在没有需要 ICU 护理的病房（病房组）接受治疗。新出现的与疾病相关的疲劳是 ICU 组中 72%的参与者和病房组中 60.3%的参与者报告的最常见症状。其次最常见的症状是呼吸困难（ICU 组 65.6%，病房组 42.6%）和心理困扰（ICU 组 46.9%，病房组 23.5%）。ICU 组中有 68.8%的人，病房组中有 45.6%的人 EQ5D 明显下降。
这是英国第一项关于出院后症状的研究。我们建议规划康复服务，以适当管理这些症状，并最大限度地提高 COVID-19 幸存者的功能恢复。
