Suppr超能文献

评估最佳健康教育计划对控制人畜共患病的影响。

Assessing the Impact of Optimal Health Education Programs on the Control of Zoonotic Diseases.

机构信息

Department of Mathematics, University of Zimbabwe, P.O. Box MP 167 Mount Pleasant, Harare, Zimbabwe.

出版信息

Comput Math Methods Med. 2020 Jul 11;2020:6584323. doi: 10.1155/2020/6584323. eCollection 2020.

Abstract

To better understand the dynamics of zoonotic diseases, we propose a deterministic mathematical model to study the dynamics of zoonotic brucellosis with a focus on developing countries. The model contains all the relevant biological details, including indirect transmission by the environment. We analyze the essential dynamic behavior of the model and perform an optimal control study to design effective prevention and intervention strategies. The sensitivity analysis of the model parameters is performed. The aim of the controls is tied to reducing the number of infected humans, through health promotional programs within the affected communities. The Pontryagin's Maximum Principle is used to characterize the optimal level of the controls, and the resulting optimality system is solved numerically. Overall, the study demonstrates that through health promotional programs on zoonotic diseases among villagers, it is vital that they should be conducted with high efficacy.

摘要

为了更好地了解人畜共患病的动态,我们提出了一个确定性的数学模型,研究以发展中国家为重点的人畜共患布鲁氏菌病的动态。该模型包含了所有相关的生物学细节,包括环境的间接传播。我们分析了模型的基本动态行为,并进行了最优控制研究,以设计有效的预防和干预策略。对模型参数进行了敏感性分析。控制的目的是通过受影响社区内的健康促进计划,减少感染人类的数量。庞特里亚金极大值原理用于描述控制的最优水平,所得最优性系统通过数值方法求解。总的来说,这项研究表明,通过在村民中开展针对人畜共患病的健康促进计划,至关重要的是,这些计划应该具有很高的效果。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验