Wilson J A, Deary I J, Maran A G
University of Edinburgh Department of Otolaryngology.
Br J Psychiatry. 1988 Sep;153:335-9. doi: 10.1192/bjp.153.3.335.
Forty-six patients, 9 male, 37 female, presenting to an ear, nose and throat department with a principal complaint of globus sensation were investigated by radiology, manometry, endoscopy and prolonged ambulatory pH monitoring to exclude a physical basis for their symptoms. Patients also underwent assessment by the Eysenck Personality Inventory (EPI) and General Health Questionnaire (GHQ). The only organic abnormalities detected were an abnormal degree of oesophageal acid exposure (seven patients) and oesophageal spasm (one patient). Female patients were neurotic introverts on EPI testing; males were stable ambiverts. High GHQ scores were present in 13 females (35%) and one male and there was a significant correlation between N scores (in the EPI) and GHQ scores. We propose that globus is a useful, single-symptom model for the study of conversion disorders.
46例以咽部异物感为主诉就诊于耳鼻喉科的患者，9例男性，37例女性，接受了放射学、测压、内镜检查及长时间动态pH监测，以排除其症状的生理基础。患者还接受了艾森克人格问卷（EPI）和一般健康问卷（GHQ）评估。仅检测到的器质性异常为食管酸暴露程度异常（7例患者）和食管痉挛（1例患者）。女性患者在EPI测试中为神经质内向型；男性为稳定中间型。13名女性（35%）和1名男性的GHQ得分较高，且EPI中的N得分与GHQ得分之间存在显著相关性。我们认为，咽部异物感是研究转换障碍的一个有用的单一症状模型。
