Shen Jenny I, Chen Lucia, Vangala Sitaram, Leng Lynn, Shah Anuja, Saxena Anjali B, Perl Jeffrey, Norris Keith C
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA.
Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Kidney Med. 2020 Feb 11;2(2):105-115. doi: 10.1016/j.xkme.2019.11.006. eCollection 2020 Mar-Apr.
RATIONALE & OBJECTIVE: Home dialysis has been underused in the United States, especially among minority groups. We investigated whether adjustment for socioeconomic factors would attenuate racial/ethnic differences in the initiation of home dialysis.
Retrospective observational cohort study.
SETTING & POPULATION: Adult patients in the US Renal Data System who initiated dialysis on day 1 with either in-center hemodialysis (HD), home HD (HHD), or peritoneal dialysis (PD) from 2005 to 2013.
Race/ethnicity: non-Hispanic white, Hispanic, black, or Asian.
Initiating dialysis with PD versus in-center HD and HHD versus in-center HD for each minority group compared with non-Hispanic whites.
Odds ratios and 95% CIs estimated by logistic regression.
Of 523,526 patients, 55% were white, 28% were black, 13% were Hispanic, and 4% were Asian; 8% started dialysis on PD, and 0.1%, on HHD. In unadjusted analyses, blacks and Hispanics were 30% and 19% less likely and Asians were 31% more likely to start on PD than whites. The differences narrowed when fully adjusted for demographic, medical, and socioeconomic factors. Adjustment for socioeconomic factors reduced these differences between white and black, Hispanic, and Asian patients by 13%, 28%, and 1%, respectively. Blacks were just as likely and Hispanics and Asians were less likely to start on HHD than whites. This did not change appreciably when fully adjusted for demographic, medical, and socioeconomic factors.
No data for physician and patient preferences or modality education.
Black and Hispanic patients are less likely to start on PD than white patients, attributable partly, though not completely, to socioeconomic factors. Hispanics and Asians are less likely to start on HHD than whites. This was materially unaffected by socioeconomic factors. More research is needed to determine whether urgent-start PD programs and transitional care units in socioeconomically disadvantaged areas might reduce these disparities and increase home dialysis use among all groups.
家庭透析在美国的利用率一直较低,尤其是在少数族裔群体中。我们调查了调整社会经济因素是否会减弱家庭透析起始阶段的种族/民族差异。
回顾性观察队列研究。
美国肾脏数据系统中2005年至2013年第1天开始透析的成年患者,透析方式为中心血液透析(HD)、家庭血液透析(HHD)或腹膜透析(PD)。
种族/民族:非西班牙裔白人、西班牙裔、黑人或亚裔。
每个少数族裔群体与非西班牙裔白人相比,起始透析采用PD而非中心HD以及HHD而非中心HD的情况。
通过逻辑回归估计比值比和95%置信区间。
在523,526名患者中,55%为白人,28%为黑人,13%为西班牙裔,4%为亚裔;8%开始采用PD透析,0.1%开始采用HHD透析。在未调整分析中,黑人、西班牙裔开始采用PD透析的可能性分别比白人低30%和19%,亚裔比白人高31%。在对人口统计学、医学和社会经济因素进行完全调整后,差异缩小。对社会经济因素进行调整后,白人与黑人、西班牙裔和亚裔患者之间的这些差异分别减少了13%、28%和1%。黑人开始采用HHD透析的可能性与白人相同,西班牙裔和亚裔比白人低。在对人口统计学、医学和社会经济因素进行完全调整后,这种情况没有明显变化。
没有关于医生和患者偏好或透析方式教育的数据。
黑人及西班牙裔患者起始采用PD透析的可能性低于白人患者,部分原因(但并非全部)是社会经济因素。西班牙裔和亚裔起始采用HHD透析的可能性低于白人。社会经济因素对此影响不大。需要更多研究来确定社会经济条件不利地区的紧急启动PD项目和过渡护理单元是否可以减少这些差异并增加所有群体对家庭透析的使用。