Matthews N C, Corser G
Department of Anaesthetics, Birmingham Maternity Hospital, Edgbaston.
Anaesthesia. 1988 Sep;43(9):783-5. doi: 10.1111/j.1365-2044.1988.tb05758.x.
This study assesses the efficacy of epidural fentanyl in the relief of shaking associated with epidural analgesia. Fifty mothers whose shaking was sufficient to cause distress were divided randomly to receive either fentanyl 25 micrograms in 5 ml sterile normal saline or 5 ml of saline through their in-situ epidural. Shaking stopped within 15 minutes in 18 out of 25 (72%) of those given fentanyl but in only 4 out of 25 (16%) of the saline group and this is statistically significant (p less than 0.01). Fentanyl can be recommended in this context.
本研究评估硬膜外给予芬太尼缓解硬膜外镇痛相关寒战的疗效。50名寒战严重到引起不适的产妇被随机分为两组,一组通过硬膜外导管给予5毫升无菌生理盐水中含25微克芬太尼,另一组给予5毫升生理盐水。给予芬太尼的25名产妇中有18名(72%)在15分钟内寒战停止,而生理盐水组25名产妇中只有4名(16%)寒战停止,差异具有统计学意义(p<0.01)。在此情况下,可推荐使用芬太尼。