Trab Trine, Nielsen René Ernst, Frøkjær Jens Brøndum, Jensen Svend Eggert
Ugeskr Laeger. 2020 Jul 27;182(31).
Coronary artery disease is a major contributor to increased mortality rates in patients with schizophrenia in whom less treatment of cardiovascular (CV) risk factors is seen. Risk prediction models used in the general population are not sufficient to predict CV mortality in patients with schizophrenia. Measurement of calcium score (CACS) by cardiac CT-scan improves risk prediction in the general population, but has not been investigated in patients with schizophrenia. CACS might contribute to improved CV risk assessment and treatment in these patients and further studies should address this.
冠状动脉疾病是精神分裂症患者死亡率增加的主要因素,这类患者对心血管(CV)危险因素的治疗较少。一般人群中使用的风险预测模型不足以预测精神分裂症患者的心血管死亡率。通过心脏CT扫描测量钙评分(CACS)可改善一般人群的风险预测,但尚未在精神分裂症患者中进行研究。CACS可能有助于改善这些患者的心血管风险评估和治疗,进一步的研究应关注这一点。