Bennett T O, Peyman G A
Ophthalmic Surg. 1977 Apr;8(2):42-8.
To determine the effect of histocompatibility matching and mismatching at the rabbit leukocyte-locus A (RL-A locus) on graft survival in rabbits, we created a model to enhance graft failure. Rabbit corneas received alkali burns with consequent vascularization of the graft bed. Each rabbit underwent large (10-mm) penetrating keratoplasty and simultaneous lens extraction. Grafts in four of six corneas from the matched group remained transparent for the extent of the experiment; none of the grafts in the mismatched group were transparent at the end of the experiment.
为了确定兔白细胞A位点（RL - A位点）组织相容性匹配与不匹配对兔移植物存活的影响，我们建立了一个促进移植物失败的模型。兔角膜接受碱烧伤，随后植床血管化。每只兔均接受大直径（10毫米）穿透性角膜移植术并同时进行晶状体摘除术。在实验期间，匹配组六只角膜中的四只移植物保持透明；不匹配组的移植物在实验结束时均不透明。
