Kaushik Atul, Wani Showkat Nazir, Baba Muneer Ahmad, Agarwal A K
Post Graduate Resident, SMS and R, Sharda University, Greater Noida, Uttar Pradesh.
SR, SMS and R, Sharda University, Greater Noida, Uttar Pradesh.
J Assoc Physicians India. 2020 Aug;68(8):73-75.
Coronavirus disease 2019 (COVID 2019) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is observed to cause liver dysfunction. We aimed to observe abnormal liver function tests (LFTs) in COVID-19 patients admitted in our hospital.
It was a cross- sectional study involving 105 COVID-19 patients who were admitted in our Hospital from 03-04-2020 to 02-05-2020. The COVID-19 positivity was defined on basis of real-time PCR. Thorough clinical examination and laboratory investigations including Complete Blood Count, Renal function Tests, Liver Function Tests, Chest X-ray, ECG, etc. were done.
The total number of male and female patients were 64 and 41. Out of total 105 patients, 62 i.e. 59.04% had abnormal LFTs at time of admission. Out of these 62 patients, 44(70.9%) were Male and 18(29.03%) were female. Only 5(4.76%) patients had abnormal LFTs on repeat testing. Median Age of patients was 33years. Average stay of patients with Abnormal LFTs was 15 days (10-16 days) as compared to 10 days (7-11days) for patients with normal LFTs.
The prevalence of Abnormal Liver function tests in patients of COVID-19 is 59.04%. Abnormal liver functions were more in males. The average stay in hospital for COVID-19 patients with abnormal LFTs was longer than those with normal LFTs.
观察到由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的2019冠状病毒病（COVID-19）疫情会导致肝功能障碍。我们旨在观察我院收治的COVID-19患者的肝功能检查异常情况。
这是一项横断面研究，涉及2020年4月3日至2020年5月2日在我院收治的105例COVID-19患者。根据实时聚合酶链反应确定COVID-19阳性。进行了全面的临床检查和实验室检查，包括全血细胞计数、肾功能检查、肝功能检查、胸部X光、心电图等。
男性和女性患者总数分别为64例和41例。在105例患者中，62例（即59.04%）在入院时肝功能检查异常。在这62例患者中，44例（70.9%）为男性，18例（29.03%）为女性。重复检测时只有5例（4.76%）患者肝功能检查异常。患者的中位年龄为33岁。肝功能检查异常的患者平均住院时间为15天（10 - 16天），而肝功能检查正常的患者平均住院时间为10天（7 - 11天）。
COVID-19患者肝功能检查异常的患病率为59.04%。男性肝功能异常更为常见。肝功能检查异常的COVID-19患者平均住院时间比肝功能检查正常的患者更长。
