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牛同种抗血清中存在抗绵羊淋巴细胞的抗体。

Antibodies to ovine lymphocytes exist in bovine alloantisera.

作者信息

Stear M J, Outteridge P M, Dufty J H, Nicholas F W, Tucker E M

机构信息

Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra.

出版信息

Exp Clin Immunogenet. 1986;3(1):28-33.

PMID:3274045
Abstract

Forty-six percent of 149 reagents against class 1 antigens of the bovine major histocompatibility system reacted with lymphocytes from 1 or more sheep in a microlymphocytotoxicity test. The reactions fell into six groups. The majority of antisera defined an antigen present on both erythrocytes and lymphocytes. This antigen is probably the R blood group antigen and the reactions were unrelated to the presence of anticlass I activity and are probably due to the additional presence of antibodies of R specificity. The other antigens are not identical to any of the 14 red blood cell factors or seven lymphocyte antigens examined, nor did they correspond to any of the class I bovine lymphocyte antigens defined by the alloantisera.

摘要

在一项微淋巴细胞毒性试验中,针对牛主要组织相容性系统1类抗原的149种试剂中有46%与来自1只或更多只绵羊的淋巴细胞发生反应。这些反应分为六组。大多数抗血清确定了一种存在于红细胞和淋巴细胞上的抗原。这种抗原可能是R血型抗原,这些反应与抗1类活性的存在无关,可能是由于额外存在R特异性抗体。其他抗原与所检测的14种红细胞因子或7种淋巴细胞抗原中的任何一种都不相同,也与同种抗血清所定义的任何1类牛淋巴细胞抗原不对应。

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