Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mycoses. 2020 Oct;63(10):1033-1046. doi: 10.1111/myc.13153. Epub 2020 Aug 23.
This review summarises both the recent and relevant studies about cryptococcal infections in haematologic malignancies and haematopoietic stem cell transplantation. Although uncommon in this patient population, this infection carries a high mortality, especially if left untreated. Given the limited data, we draw some conclusions with respect to management from the solid organ transplantation and HIV-infected literature. Herein, we discuss cryptococcosis with a particular attention to its background, epidemiology, risk factors, clinical presentation, diagnosis, treatment and prevention in this group.
本综述总结了血液恶性肿瘤和造血干细胞移植患者中近期和相关的隐球菌感染研究。虽然在该患者人群中并不常见，但如果不治疗，这种感染的死亡率很高。鉴于数据有限，我们从实体器官移植和 HIV 感染文献中得出了一些关于管理的结论。本文讨论了隐球菌病，特别关注其背景、流行病学、危险因素、临床表现、诊断、治疗和预防。
