Endocrinology Department VI, "C.I.Parhon" National Institute of Endocrinology, 34-36 Aviatorilor Boulevard, Bucharest 011863, Romania. Electronic address: https://twitter.com/the_hormone_doc.
Neurosurgery Department, Reference Center for Rare Pituitary Diseases HYPO, "Groupement Hospitalier Est" Hospices Civils de Lyon, "Claude Bernard" Lyon 1 University, Hôpital Pierre Wertheimer, 59 Pinel Boulevard, Lyon, Bron 69677, France.
Endocrinol Metab Clin North Am. 2020 Sep;49(3):505-515. doi: 10.1016/j.ecl.2020.05.008. Epub 2020 Jul 8.
A subset of pituitary tumors present an aggressive behavior that remains difficult to predict, and in rare cases they metastasize. The current European Society for Endocrinology (ESE) guidelines for the management of aggressive pituitary tumors and carcinomas provide valuable guidance, but several issues remain unaddressed because of the scarcity of data in the literature. This article presents key clinical aspects regarding aggressive pituitary tumors and carcinomas, and also discusses some of the unanswered questions of the ESE guidelines, focusing on both diagnosis and treatment.
一部分垂体肿瘤表现出侵袭性行为,这种行为仍然难以预测,在极少数情况下,它们会转移。目前欧洲内分泌学会(ESE)关于侵袭性垂体肿瘤和癌的管理指南提供了有价值的指导,但由于文献中数据的缺乏,仍有几个问题没有得到解决。本文介绍了侵袭性垂体肿瘤和癌的一些关键临床方面,并讨论了 ESE 指南中一些未解决的问题,重点是诊断和治疗。