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晚期痴呆患者经皮内镜下胃造口管拔除术:病例系列研究

Percutaneous Endoscopic Gastrostomy Tube Removal for Patients With Advanced Dementia: Case Series Study.

作者信息

Hattori Yukari, Kojima Taro, Komura Hiroaki, Ura Nobuyuki, Akishita Masahiro

机构信息

Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Sapporo Nishimaruyama Hospital, Sapporo, Japan.

出版信息

Ann Geriatr Med Res. 2019 Mar;23(1):27-30. doi: 10.4235/agmr.19.0006. Epub 2019 Mar 31.

DOI:10.4235/agmr.19.0006
PMID:32743282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7387600/
Abstract

BACKGROUND

Although the notion of percutaneous endoscopic gastrostomy (PEG) tube placement for patients with dementia has been changing, the number of cases of PEG placement remains high as Japan has become a super-aged society. However, there is insufficient research about the clinical course of dementia patients with PEG, especially regarding PEG extubation after regaining full oral intake. This case series aimed to reveal the demographic data of patients who successfully underwent PEG extubation and to identify clinical factors that might help predict eventual resumption.

METHODS

This retrospective case series was identified in a private, community-based long-term care hospital in Sapporo, Japan. Inclusion criteria for the series were: 1) age, ≥75 years, 2) diagnosis of any type of dementia, and 3) resumption of full oral intake after removal of PEG tubes.

RESULTS

Eight female patients were identified. Decreased oral intake was triggered by acute medical conditions, such as infectious enteritis. A trial of oral intake was initiated mostly by speech therapists. A majority of the patients ate pureed food. The patients aged ≥85 years with advanced dementia could be weaned from PEG tubes.

CONCLUSION

The series indicates that even patients with limited life expectancy could recover swallowing function by receiving appropriate guidance and care. Constant evaluation for swallowing function even after PEG insertion may be important for PEG extubation.

摘要

背景

尽管针对痴呆患者进行经皮内镜下胃造口术(PEG)置管的观念一直在变化,但随着日本进入超老龄化社会,PEG置管的病例数仍然居高不下。然而,关于PEG痴呆患者的临床病程,尤其是恢复完全经口进食后PEG拔管方面的研究不足。本病例系列旨在揭示成功进行PEG拔管患者的人口统计学数据,并确定可能有助于预测最终恢复经口进食的临床因素。

方法

本回顾性病例系列来自日本札幌一家私立的、基于社区的长期护理医院。该系列的纳入标准为:1)年龄≥75岁;2)诊断为任何类型的痴呆;3)PEG管拔除后恢复完全经口进食。

结果

共确定了8名女性患者。经口摄入量减少是由急性疾病引发的,如感染性肠炎。经口进食试验大多由言语治疗师发起。大多数患者食用泥状食物。年龄≥85岁且患有晚期痴呆症的患者可以拔除PEG管。

结论

该系列表明,即使预期寿命有限的患者,通过接受适当的指导和护理也可以恢复吞咽功能。即使在PEG置管后持续评估吞咽功能对于PEG拔管可能也很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48b6/7387600/dbb432e6940a/agmr-23-027f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48b6/7387600/dbb432e6940a/agmr-23-027f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48b6/7387600/dbb432e6940a/agmr-23-027f1.jpg

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本文引用的文献

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Guidelines from the Japan Geriatrics Society for the decision-making processes in medical and long-term care for the elderly: Focusing on the use of artificial hydration and nutrition.日本老年医学会关于老年人医疗和长期护理决策过程的指南:聚焦人工补液和营养的使用
Geriatr Gerontol Int. 2018 Jun;18(6):823-827. doi: 10.1111/ggi.13441.
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The Effects of Percutaneous Endoscopic Gastrostomy on Quality of Life in Patients With Dementia.经皮内镜下胃造口术对痴呆患者生活质量的影响。
Gastroenterology Res. 2012 Feb;5(1):10-20. doi: 10.4021/gr392w. Epub 2012 Jan 20.
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PEG Insertion in Patients With Dementia Does Not Improve Nutritional Status and Has Worse Outcomes as Compared With PEG Insertion for Other Indications.
与因其他适应症进行经皮内镜下胃造口术(PEG)相比,痴呆患者进行PEG并不能改善营养状况,且预后更差。
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End-of-life issues in advanced dementia: Part 2: management of poor nutritional intake, dehydration, and pneumonia.晚期痴呆症患者的临终问题:第2部分:营养摄入不足、脱水及肺炎的管理
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The role of gastrostomy tube placement in advanced dementia with dysphagia: a critical review.胃造口管置入在晚期痴呆伴吞咽困难中的作用:一项批判性综述。
Clin Interv Aging. 2014 Oct 14;9:1733-9. doi: 10.2147/CIA.S53153. eCollection 2014.
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Complication and mortality rate after percutaneous endoscopic gastrostomy are low and indication-dependent.经皮内镜下胃造口术后的并发症和死亡率较低,且取决于适应证。
Scand J Gastroenterol. 2014 Jul;49(7):891-8. doi: 10.3109/00365521.2014.916343. Epub 2014 Jun 4.
8
Survival of geriatric patients after percutaneous endoscopic gastrostomy in Japan.日本经皮内镜胃造口术老年患者的生存情况。
World J Gastroenterol. 2010 Oct 28;16(40):5084-91. doi: 10.3748/wjg.v16.i40.5084.
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Possibility of oral feeding after induction of percutaneous endoscopic gastrostomy.经皮内镜胃造瘘术后进行口服喂养的可能性。
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Resumption of oral intake following percutaneous endoscopic gastrostomy.经皮内镜胃造瘘术后恢复口服摄入。
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