Murphy Lynne M, Lipman Timothy O
Gastroenterology/ Hepatology/Nutrition Section, Veterans Affairs Medical Center, Washington, DC 20422, USA.
Arch Intern Med. 2003 Jun 9;163(11):1351-3. doi: 10.1001/archinte.163.11.1351.
Artificial feeding by a percutaneous endoscopic gastrostomy (PEG) tube in patients with dementia has increased since the introduction of the endoscopic method of tube placement. Few studies have documented survival benefit from this intervention. This report reviews our experience with PEG tube placement for feeding patients with dementia.
All consultations for PEG tube placement were evaluated by a certified nutrition support nurse (L.M.M.) in consultation with a member of the gastroenterology physician staff (T.O.L.) for 24 months. Evaluation included the attainment of a brief medical history, a physical examination, and a review of comorbid conditions, laboratory variables for nutrition status, and bleeding risk. Interviews with patients or surrogates were conducted, including an explanation of the risks and benefits of PEG tube placement. A Kaplan-Meier survival curve was used to compare the median survival between patients with dementia who received a PEG tube and patients with dementia in whom PEG tube placement was refused.
We received 41 consultations for PEG tube placement in patients with dementia. Percutaneous endoscopic gastrostomy was performed in 23 patients; 18 patients met the medical criteria for PEG tube placement, but surrogates refused placement. The median survival for the 23 patients who underwent PEG was 59 days; the median survival for the 18 patients who did not undergo PEG was 60 days.
There seems to be no survival benefit in patients with dementia who receive artificial feeding by a PEG tube.
自从经皮内镜下胃造口术(PEG)置管方法引入以来,痴呆患者通过PEG管进行人工喂养的情况有所增加。很少有研究记录这种干预措施对生存的益处。本报告回顾了我们为痴呆患者进行PEG管置管的经验。
在24个月内,所有PEG管置管咨询均由一名获得认证的营养支持护士(L.M.M.)与一名胃肠病学医师(T.O.L.)共同评估。评估内容包括获取简要病史、进行体格检查、审查合并症、营养状况的实验室指标以及出血风险。对患者或代理人进行了访谈,包括解释PEG管置管的风险和益处。使用Kaplan-Meier生存曲线比较接受PEG管的痴呆患者与拒绝PEG管置管的痴呆患者的中位生存期。
我们收到了41例痴呆患者的PEG管置管咨询。23例患者接受了经皮内镜下胃造口术;18例患者符合PEG管置管的医学标准,但代理人拒绝置管。接受PEG的23例患者的中位生存期为59天;未接受PEG的18例患者的中位生存期为60天。
通过PEG管进行人工喂养的痴呆患者似乎没有生存益处。