Golsorkhtabaramiri Mohammad, Inderjeeth Charles A
Department of Rehabilitation and Aged Care, Sir Charles Gairdner Hospital, North Metropolitan Health Service, Perth, Australia.
School of Medicine, University of Western Australia, Crawley, Perth, Australia.
Ann Geriatr Med Res. 2020 Mar;24(1):50-54. doi: 10.4235/agmr.19.0046. Epub 2020 Mar 24.
A 78-year-old woman presented with an atypical femoral fracture of her right femur associated with a left thigh stress fracture following 9 years of bisphosphonate therapy. The fracture was managed with femoral nailing. However, she represented 3 years later with peri-prosthetic infection, worsening of the left-side stress fracture, and low bone turnover in a bone metabolic study, consistent with an ongoing bisphosphonate effect. This case highlights the increased rate of postoperative complications in atypical femoral fractures even years after surgery as well as the challenging management issues for contralateral fracture and the risk of missing bilateral fractures.
一名78岁女性在接受9年双膦酸盐治疗后,出现右股骨非典型骨折,并伴有左大腿应力性骨折。骨折采用股骨钉固定治疗。然而,3年后她再次就诊,出现假体周围感染、左侧应力性骨折加重,且骨代谢研究显示骨转换率低,这与双膦酸盐的持续作用一致。该病例突出了非典型股骨骨折术后数年并发症发生率增加的问题,以及对侧骨折的挑战性管理问题和漏诊双侧骨折的风险。