Choi Hoon, Kim Yong Il, Na Chan Ho, Kim Min Sung, Shin Bong Seok
Department of Dermatology, Chosun University College of Medicine, Gwangju, Korea.
Ann Geriatr Med Res. 2020 Jun;24(2):148-151. doi: 10.4235/agmr.20.0012. Epub 2020 Jun 5.
is an encapsulated yeast that can be found in pigeon droppings, hay, and dust. Primary cutaneous cryptococcosis (PCC) without systemic involvement is recognized as a distinct clinical condition and is rarely reported in immunocompetent patients. A 78-year-old woman with no history of other diseases except for hypertension presented with a painful diffuse erythematous plaque along with oozing on left forearm that had lasted for 7 weeks. She was treated with cefoperazone/sulbactam for 3 weeks under suspicion of bacterial cellulitis, although the lesions aggravated without any improvement. We performed bacterial and fungal cultures as well as incisional biopsy. The pathogen was identified as following sequence analysis of the internal transcribed spacer gene. The patient was treated with fluconazole 400 mg/day for 3 months, and there was no evidence of recurrence after 3 months of follow-up.
是一种包囊酵母菌，可在鸽粪、干草和灰尘中发现。无全身受累的原发性皮肤隐球菌病（PCC）被认为是一种独特的临床病症，在免疫功能正常的患者中很少有报道。一名78岁女性，除高血压外无其他疾病史，左前臂出现疼痛性弥漫性红斑斑块并伴有渗出，持续7周。因怀疑细菌性蜂窝织炎，她接受了3周的头孢哌酮/舒巴坦治疗，但病变加重且无任何改善。我们进行了细菌和真菌培养以及切开活检。经内部转录间隔区基因序列分析，病原体被鉴定为 。患者接受了每天400毫克氟康唑治疗3个月，随访3个月后无复发迹象。
